Long-term, dose-controlled vagus nerve stimulation (VNS) is feasible in mice using a multi-lab validated implantation procedure, allowing therapeutic testing of VNS in many disease models.
A robust procedure to purify mRNAs and their associated proteins identify CFB2 as the critical protein that binds and influences the fate of the main virulence factor in Trypanosoma brucei.
Forces stemming from cell-matrix adhesions, but not cell-cell adhesions, are directly transmitted to the nuclear lamina to regulate epidermal cell fate.
Circuit tracing and in vivo calcium imaging reveals neurons conveying polarized light information from photoreceptors to the central brain, transforming patterns in the sky into a directional cue for navigation.
A protein-bounded organelle-like compartment from Synechococcus elongatus PCC 7942 is upregulated under sulfur starvation and contains a cysteine desulfurase cargo enzyme.
Injuries activate the oral identity-specifying canonical Wnt signaling pathway in Hydra, which can trigger head regeneration in permissive tissue contexts created by the absence of pre-existing organizers.