Redundant pathways prevent heterochromatin spreading and ectopic heterochromatin assembly; and plasticity of heterochromatin assembly allows cells to adapt to heterochromatin stress.

Conserved transcriptomic profile of uropathogenic E. coli in patients identifies an infection-specific metabolic state.

Hysteretic switching between virulence states has been observed in a human pathogen.

A putative histone demethylase in fission yeast has non-enzymatic properties that regulates heterochromatin assembly and epigenetic inheritance.

The helical rod structure and dynamic spring-like properties of the type 1 pilus are evolutionarily fine-tuned for functioning in host-pathogen interactions during urinary tract infection and gut colonization.

Yersinia pseudotuberculosis and enteropathogenic Escherichia coli promote pathogenicity by deamidating the ubiquitin-like protein NEDD8 to block ubiquitin-dependent trafficking of Perforin-2, which is an effector of innate immunity.

The formation of new neurons in the adult dentate gyrus causes a proportion of cortical neurons to transfer their existing connections to the newborn cells.

H3K23me3 is a RNAi-mediated transgenerationally heritable heterochromatin mark in Caenorhabditis elegans.

The phosphorylation of tyrosine in the heptad repeat of the C-terminal domain of the largest subunit of RNA polymerase II promotes Ser2 phosphorylation by P-TEFb for pausing release.

A novel method predicts cancer and immune cell types from bulk tumor gene expression data with the ability to consider uncharacterized and possibly highly variable cell types, which is validated in human genome.