Ceapins specifically inhibit ATF6α signaling by preventing its transport to the Golgi during endoplasmic reticulum stress.

Ceapins enable selective pharmacological inhibition of the cytoprotective transcriptional response to endoplasmic reticulum stress through ATF6α without affecting other branches of the unfolded protein response.

A binary cell fate decision to be or not to be stomata is regulated by multiple peptide ligands, each triggering a unique subcellular dynamics of their shared receptor.

Knockoff is a tool for researchers who wish to acutely disrupt a membrane protein.

Super-resolution microscopy sets a new strategy to comprehend the membrane organization of γ-secretase at single complex resolution identifying nanodomain associations and its diffusion in situ in the living membrane.

The co-chaperone CHORDC1 is specifically required for epidermal growth factor receptor trafficking and signaling in Caenorhabditis elegans and in human cells.

A detailed molecular mechanism on lipid flipping from outside leaflet to the inside leaflet of the eukaryotic plasma membrane bilayer.

eMags is an engineered photodimerizer pair for optogenetic modulation in mammalian cells that is especially suited for the manipulation of intracellular processes occurring in small volumes or subcellular organelles.

Dendritic cell recognition and processing of antigens from dead cells, utilising the Clec9A-damage recognition receptor, is controlled by a novel RNF41-ubiquitin-mediated regulatory pathway.

Apical membrane remodeling in a resorptive Drosophila epithelium generates a shared multinuclear cytoplasm.