10 results found
    1. Structural Biology and Molecular Biophysics

    Recruitment of two dyneins to an mRNA-dependent Bicaudal D transport complex

    Thomas E Sladewski et al.
    mRNA cargo orchestrates the activation of an in vitro reconstituted dynein-dynactin-Bicaudal D-Egalitarian complex for robust processive motion on microtubules.
    1. Cell Biology

    RNA-directed activation of cytoplasmic dynein-1 in reconstituted transport RNPs

    Mark A McClintock et al.
    Reconstitution of dynein-based mRNA transport with purified components reveals a pivotal role of an RNA localisation signal in controlling the assembly and activity of the translocation machinery.
    1. Ecology
    2. Evolutionary Biology

    Eco-evolutionary dynamics of nested Darwinian populations and the emergence of community-level heredity

    Guilhem Doulcier et al.
    Artificial selection on communities drives the evolution of interactions and establishes community-level inheritance.
  1. Living Science: Power analysis

    Indira M Raman
    After acknowledging that power differentials exist, can scientists find inspiration to persevere anyway?
    1. Cell Biology

    The influence of dynein processivity control, MAPs, and microtubule ends on directional movement of a localising mRNA

    Harish Chandra Soundararajan, Simon L Bullock
    In vitro reconstitution of mRNA motility reveals the basis of directionally biased motion by groups of motors, their response to potential obstacles, and the consequences of reaching microtubule ends.
    1. Evolutionary Biology

    Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates

    Rylan Shearn et al.
    A larger non-recombining region in sexually dimorphic primates compared to sexually monomorphic ones supports the view that sexually antagonistic mutations have influenced the evolution of sex chromosomes in primates.
    1. Epidemiology and Global Health
    2. Medicine

    Do wealth and inequality associate with health in a small-scale subsistence society?

    Adrian V Jaeggi et al.
    Socio-economic hierarchies may be bad for health, even among people living in a relatively traditional, small-scale society in the Bolivian Amazon.
    1. Cell Biology

    CYK-4 functions independently of its centralspindlin partner ZEN-4 to cellularize oocytes in germline syncytia

    Kian-Yong Lee et al.
    The CYK-4 subunit of the broadly conserved intercellular bridge component centralspindlin, but not its ZEN-4 subunit, is essential for the cytokinesis-like closure of intercellular bridges that cellularizes oocytes to separate them from germline syncytia.
    1. Cell Biology

    The human cytoplasmic dynein interactome reveals novel activators of motility

    William B Redwine et al.
    Using a proximity-dependent labeling approach in living cells, the human cytoplasmic dynein-1 interactome was identified and a new family of dynein activators, ninein and ninein-like, was discovered.
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    Making (neuro)science accessible world-wide: Online seminars for the globe

    World Wide Neuro reconnects researchers and facilitates scientific discourse in the times of the pandemic.

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