The ventrolateral striatum is found to be recruited during the encoding of cocaine preference, within which Egr2-expressing ensembles are functionally important, as is the expression of Egr2 within them.

Epithelial tumors secrete the ER-resident AGR2 in the extracellular matrix to function as a novel essential microenvironmental regulator of epithelial tissue architecture, which leads to tumorigenicity.

The dynamic homeostasis of the planarian epidermis serves as an experimental paradigm to study stem cell dynamics and post-mitotic specification of diverse functional cell fates.

Combined single nucleus RNAseq and ATACseq enabled the first molecular resolution of all hindbrain rhombomeres, the derivation of a unique gene regulatory network for each rhombomere, and the identification of gene expression changes as rhombomeres form from early progenitor pools.

A new luciferase and fluorescent reporter system enables rapid and efficient in-cell profiling of the majority of protein kinase oncogenes known to date.

Inducible transcription in the brain encodes detailed aspects of recent experience.

The maize CLAVATA receptor, FEA2, functions in the perception of two different ligands, and remarkably that signaling from these different inputs is differentiated by the receptor interacting with two different downstream components.

Single-cell multiomics reveals the gene regulatory networks and enhancer logic underlying two distinct wound response cell states in the Drosophila wing imaginal disc and finds similarities with cell states observed in the Ras-scrib tumor model.

A unique, widely distributed gut bacterial enzyme selectively metabolizes plant-derived cardiac glycoside drugs.