Browse the search results

Page 2 of 17
  1. Eph and Ephrin function in dispersal and epithelial insertion of pigmented immunocytes in sea urchin embryos

    Oliver A Krupke, Ivona Zysk ... Robert D Burke
    Eph receptor signaling commonly excludes migrating embryonic cells from regions of high ligand density; however, in sea urchin embryos pigmented immunocytes are attracted to regions expressing high levels of Ephrin.
    1. Computational and Systems Biology
    2. Neuroscience

    A molecular mechanism for the topographic alignment of convergent neural maps

    Elise Savier, Stephen J Eglen ... Michael Reber
    Retinal ephrin-As gradients provide positional information, through retino-collicular map in the superior colliculus, for topographic alignment of cortico-collicular projections.
    1. Structural Biology and Molecular Biophysics

    A novel pH-dependent membrane peptide that binds to EphA2 and inhibits cell migration

    Daiane S Alves, Justin M Westerfield ... Francisco N Barrera
    The transmembrane domain of the EphA2 receptor has been transformed into a novel amphitropic peptide that binds to the EphA2 receptor and inhibits cell migration.
    1. Structural Biology and Molecular Biophysics

    Specific Eph receptor-cytoplasmic effector signaling mediated by SAM–SAM domain interactions

    Yue Wang, Yuan Shang ... Mingjie Zhang
    Comparative structural studies reveal how the cytoplasmic tails of Eph receptors can differentiate different downstream target proteins via highly specific SAM–SAM domain interactions.
    1. Cell Biology
    2. Developmental Biology

    Ephrin-B1 regulates the adult diastolic function through a late postnatal maturation of cardiomyocyte surface crests

    Clement Karsenty, Celine Guilbeau-Frugier ... Celine Galés
    Eprhin B1 in the cardiomyocyte regulates the maturation of the adult surface crest architecture and of the diastolic function during a late postnatal stage in rodents.
    1. Cell Biology
    2. Developmental Biology

    Ingression-type cell migration drives vegetal endoderm internalisation in the Xenopus gastrula

    Jason WH Wen, Rudolf Winklbauer
    The cellular behaviours that underlie the internalization of the multilayered endoderm anlage in Xenopus laevis link the ancestral mode of vertebrate gastrulation to common, epithelial-based mechanisms of gastrulation in non-vertebrate animals.
    1. Neuroscience

    Ephrin-B3 controls excitatory synapse density through cell-cell competition for EphBs

    Nathan T Henderson, Sylvain J Le Marchand ... Matthew B Dalva
    Competition between neurons for postsynaptic ephrin-B3 controls distribution of a limited pool of synapses and defines a novel trans-synaptic mechanism enabling neurons to set the number of synapses they receive.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    EphA7 promotes myogenic differentiation via cell-cell contact

    Laura L Arnold, Alessandra Cecchini ... DDW Cornelison
    The juxtacrine signaling molecule EphA7, when expressed on terminally-differentiated myocytes, non-cell-autonomously induces adjacent myoblasts to also commit to terminal differentiation leading to rapid coordinated differentiation across the entire population.
    1. Developmental Biology
    2. Neuroscience

    Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons

    Max Koppers, Roberta Cagnetta ... Christine E Holt
    Multiple axonal guidance receptors control the local and selective translation of mRNAs by binding to ribosomes, specific mRNAs and RNA-binding proteins.
    1. Developmental Biology
    2. Neuroscience

    NMDA receptors control development of somatosensory callosal axonal projections

    Jing Zhou, Yong Lin ... Samuel J Pleasure
    NMDAR receptors act in regulating axon guidance of somatosensory callosal projections in early postnatal life and the expression of EPHB2 receptors in target cells.