339 results found

  1. Life story: Rogier Kievit

    Having a child makes you focus on the things that truly matter.

  2. Episode 41: September 2017

    In this episode we hear about biomarkers for epilepsy, how fish can recognise faces, insect anti-anti aphrodisiacs, and why striving for novelty may hinder the progress of science.
  3. May 2016

    Episode 29: May 2016

    In this episode we hear about parasitic worms, dog tumours, epilepsy, DNA sequencing classes and social behaviour in mice.
  4. February 2017

    Episode 36: February 2017

    In this episode we hear about epilepsy, the sushi-belt model of transport in neurons, a mother in ancient Troy, the Amazon rainforest and bias in scientific reporting.
    1. Neuroscience

    A dual role for Cav1.4 Ca2+ channels in the molecular and structural organization of the rod photoreceptor synapse

    J Wesley Maddox et al.
    Ca2+ influx through Cav1.4 channels is required for the structural, but not the molecular organization of the rod photoreceptor synapse.
    1. Immunology and Inflammation

    BAD inactivation exacerbates rheumatoid arthritis pathology by promoting survival of sublining macrophages

    Jie Li et al.
    Phosphorylation-mediated inactivation of pro-apoptotic BCL-2 family protein BAD confers the apoptosis resistance on synovial sublining macrophages, thereby contributing to the development of rheumatoid arthritis.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    16p11.2 microdeletion imparts transcriptional alterations in human iPSC-derived models of early neural development

    Julien G Roth et al.
    A model of in vitro human corticogenesis identifies alterations in gene expression caused by loss of 16p11.2 CNV genes in hiPSC-derived progenitor cells.
    1. Neuroscience

    The palmitoyl acyltransferase ZDHHC14 controls Kv1-family potassium channel clustering at the axon initial segment

    Shaun S Sanders et al.
    ZDHHC14 controls palmitoylation and axon initial segment targeting of PSD93 and Kv1-family potassium channels, events that are essential for normal neuronal excitability.
    1. Neuroscience

    The effects of chloride dynamics on substantia nigra pars reticulata responses to pallidal and striatal inputs

    Ryan S Phillips et al.
    The effects of chloride homeostasis can explain diverse responses of basal ganglia output neurons to putatively inhibitory inputs and may tune these neurons' synchrony, oscillations and behavior in decision-making scenarios.
    1. Neuroscience

    All-trans retinoic acid induces synaptic plasticity in human cortical neurons

    Maximilian Lenz et al.
    The vitamin A derivative, all-trans retinoic acid, induces protein-synthesis-dependent synaptic plasticity in the human brain.
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