Predisposition to obesity-associated diseases is dependent on the ancestors' diet.

The function and distribution of kinesin motors on exocytotic vesicles is dissected and visualized through a combination of gene knockout experiments, high-resolution microscopy and advanced data analysis.

High resolution structures of the essential human AAA+ ATPase TorsinA and its disease mutant in complex with an activator reveal details of the interaction that will guide drug design and further functional characterization.

T-regulatory type 1 cells inherit a broad repertoire of epigenetic marks from T-follicular helper T-cells, offering new insights into the developmental biology of this subset.

The pathogen Acinetobacter baumannii recognises preacinetobactin not acinetobactin, yet appears likely to translocate both compounds through a mixed complex.

The Pseudomonas aeruginosa secreted signaling molecule 2'-aminoacetophenone modulates cellular immunometabolism to promote persistence in infected tissues.

A pathway directed by the KRAS oncoprotein leads to aberrant hypermethylation and transcriptional silencing of many genes including tumor suppressors, thereby promoting tumor development.

Optogenetic approaches are leading to a better understanding of the forces that determine the plane of cell division.

The pseudoenzyme CPT1C is able to sense changes in intracellular malonyl-CoA levels caused by nutrients or energy stress and regulate late endosomes/lysosomes anterograde transport, necessary for proper axon growth.

The Ca²⁺-dependence of vesicle priming, fusion, and replenishment at cerebellar mossy fiber boutons show a prominent Ca²⁺-dependent priming step, a shallow non-saturating dose-response curve up to 50 µM, and little Ca²⁺-dependence of sustained vesicle replenishment.