131 results found
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Multiple introductions of multidrug-resistant typhoid associated with acute infection and asymptomatic carriage, Kenya

    Samuel Kariuki et al.
    Carriage of MDR S. Typhi H58 sublineages that also cause acute disease provides understanding of the transmission dynamics of typhoid fever and maintenance of local pathogen populations in Kenya children.
    1. Evolutionary Biology

    Quantifying the relationship between genetic diversity and population size suggests natural selection cannot explain Lewontin’s Paradox

    Vince Buffalo
    Quantifying the relationship between census sizes and genetic diversity estimates provides insights into whether natural selection can explain the narrow range of diversity between species.
    1. Evolutionary Biology
    2. Genetics and Genomics

    A population-level invasion by transposable elements triggers genome expansion in a fungal pathogen

    Ursula Oggenfuss et al.
    The activation of transposable elements and relaxed purifying selection underpin an incipient expansion of the genome in populations of a major wheat pathogen.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Ancient Viruses: How infectious diseases arrived in the colonial Americas

    Ville N Pimenoff, Charlotte J Houldcroft
    Analysis of viral DNA from human remains suggests that the transatlantic slave trade may have introduced new pathogens that contributed to the devastating disease outbreaks in colonial Mexico.
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    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Ancient viral genomes reveal introduction of human pathogenic viruses into Mexico during the transatlantic slave trade

    Axel A Guzmán-Solís et al.
    The characterization of ancient B19V and HBV genotype A4 viruses circulating during Colonial epidemics provides new insights into the pathogens that were introduced to the Americas after the European colonization.
    1. Cell Biology

    Science Forum: Vision, challenges and opportunities for a Plant Cell Atlas

    Plant Cell Atlas Consortium et al.
    A Plant Cell Atlas that shows the location and organization of molecules at cellular and tissue levels could have far-reaching consequences for plant sciences.
    1. Ecology
    2. Microbiology and Infectious Disease

    Niche partitioning facilitates coexistence of closely related honey bee gut bacteria

    Silvia Brochet et al.
    Experiments in gnotobiotic bees and culture tubes can recapitulate gut microbiota coexistence patterns observed in nature.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    Host-associated microbe PCR (hamPCR) enables convenient measurement of both microbial load and community composition

    Derek S Lundberg et al.
    hamPCR is a cost-effective and transformative amplicon sequencing strategy to describe microbiota composition and measure its overall abundance, applicable to all samples in which host and microbial DNA are co-extracted.
    1. Plant Biology

    An oomycete effector subverts host vesicle trafficking to channel starvation-induced autophagy to the pathogen interface

    Pooja Pandey et al.
    A pathogen effector mimics starvation-induced autophagy by subverting host endomembrane trafficking to stimulate biogenesis of autophagosomes around pathogen feeding sites, revealing how pathogens interlock distinct host compartments to facilitate infection.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection

    Kunal Sharma et al.
    Live-cell imaging captures the heterogenity of bacterial growth within intracellular bacterial communities and demonstrates that the constituent bacteria are protected from clearance by antibiotics delivered with a physiologically relevant pharmacodynamic profile.

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