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Page 3 of 270
    1. Cell Biology

    6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function

    Saeed Daneshmandi, Teresa Cassel ... Pankaj Seth
    6-Phosphogluconate dehydrogenase controls regulatory T cells metabolism with shifts to Th1, Th2, and Th17 phenotypes.
    1. Neuroscience

    A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain

    Lihong Zhan, Li Fan ... Li Gan
    A hidden population of microglial progenitors with distinct transcriptomic signatures are among homeostatic microglia in adult mouse brain.
    1. Neuroscience

    The caudate nucleus contributes causally to decisions that balance reward and uncertain visual information

    Takahiro Doi, Yunshu Fan ... Long Ding
    Caudate neurons encode reward and sensory information and the effects of caudate microstimulation mimic the monkeys' voluntary reward bias strategy.
    1. Cancer Biology

    FXR1 regulates transcription and is required for growth of human cancer cells with TP53/FXR2 homozygous deletion

    Yichao Fan, Jiao Yue ... Bin Xiang
    Functional and mechanistic analyses of cancer cells containing homozygous deletion of TP53 and FXR2 reveal that inhibition of FXR1 blocks cell proliferation in a collateral lethality manner, opening an avenue to develop therapies targeting such cancers.
    1. Cell Biology

    Bardet–Biedl syndrome 3 protein promotes ciliary exit of the signaling protein phospholipase D via the BBSome

    Yan-Xia Liu, Bin Xue ... Zhen-Chuan Fan
    Bardet–Biedl syndrome 3 (BBS3) protein promotes phospholipase D to load onto the BBSome at the ciliary tip for moving out of the cilium via intraflagellar transport.
    1. Microbiology and Infectious Disease

    The Acinetobacter baumannii Mla system and glycerophospholipid transport to the outer membrane

    Cassandra Kamischke, Junping Fan ... Samuel I Miller
    An Acinetobacter baumannii ABC transporter likely facilitates transport of glycerophospholipids from the inner to the outer membrane.
    1. Neuroscience

    Reproducible, data-driven characterization of sleep based on brain dynamics and transitions from whole-night fMRI

    Fan Nils Yang, Dante Picchioni ... Jeff H Duyn
    Whole-night fMRI-based sleep classification uncovers distinct substates within N2 and REM sleep stages, along with a transition structure between them.
    1. Plant Biology

    Xanthomonas citri subsp. citri type III effector PthA4 directs the dynamical expression of a putative citrus carbohydrate-binding protein gene for canker formation

    Xinyu Chen, Huasong Zou ... Xiaojing Fan
    The putative carbohydrate-binding protein gene Cs9g12620 by PthA4-mediated induction of CsLOB1 during Xcc infection.
    1. Neuroscience

    A muscle-epidermis-glia signaling axis sustains synaptic specificity during allometric growth in Caenorhabditis elegans

    Jiale Fan, Tingting Ji ... Daniel A Colón-Ramos
    The work uncovers a muscle-epidermis-glia signaling axis, modulated by protease mig-17 and the basement membrane, that regulates synaptic allometry during growth in Caenorhabditis elegans.
    1. Neuroscience

    Convergent and divergent brain structural and functional abnormalities associated with developmental dyslexia

    Xiaohui Yan, Ke Jiang ... Fan Cao
    Convergent structural and functional brain deficits associated with dyslexia were found in left superior temporal gyrus across languages, however, language-specific deficits were also identified.