10,061 results found
  1. Peer Review: Searching for the one

    Helga Groll
    The views of peers are important when applying for a faculty position, but so are research plans and being a good 'fit'.
    1. Cancer Biology

    Reproducibility in Cancer Biology: Mixed outcomes for computational predictions

    Chi Van Dang
    Experimental efforts to validate the output of a computational model that predicts new uses for existing drugs highlights the inherently complex nature of cancer biology.
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  2. Living Science: Teaching for the future

    Indira M Raman
    Reading and discussing classic papers can be an effective way of teaching graduate students how to learn the skills they will need for a career in research.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Ion Channels: A novel origin for calcium selectivity

    Esteban Suárez-Delgado, León D Islas
    A native calcium ion channel has been identified in bacteria for the first time.
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    1. Developmental Biology

    N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration

    Elif Kon et al.
    FGFRs regulate multipolar cortical neuron orientation and the morphological change into bipolar cells in vivo under the control of N-Cadherin and the extracellular matrix protein Reelin.
    1. Ecology
    Deer mouse illustration

    The Natural History of Model Organisms: Peromyscus mice as a model for studying natural variation

    Nicole L Bedford, Hopi E Hoekstra
    The deer mouse (Peromyscus) has emerged as a model system for studying many aspects of biology, supported by extensive historical knowledge of its fascinating and varied natural history.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Fossils: A new home for microbes

    Raphael Eisenhofer, Alan Cooper
    Modern microorganisms growing in fossils provide major challenges for researchers trying to detect ancient molecules in the same fossils.
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    1. Biochemistry and Chemical Biology
    2. Cell Biology

    TOR Signaling: A central role for a region in the middle

    Edward Stuttfeld et al.
    A domain called the 'Conserved region in the middle' is responsible for target recognition in the TORC2 complex in fission yeast and the mTORC2 complex in mammals.
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    1. Cancer Biology

    Reproducibility in Cancer Biology: Small molecules remain on target for c-Myc

    Linchong Sun, Ping Gao
    Targeting the transcription factor c-Myc via one of its coactivator proteins is a promising strategy for cancer therapy.
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  3. Point of View: Strategies from UW-Madison for rescuing biomedical research in the US

    Judith Kimble et al.
    A cross-campus, cross-career stage and cross-disciplinary series of discussions at a large public university has produced a series of recommendations for addressing the problems confronting the biomedical research community in the US.

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