1,179 results found
    1. Structural Biology and Molecular Biophysics

    Encounter complexes and dimensionality reduction in protein–protein association

    Dima Kozakov et al.
    Analysis of protein–protein encounter complexes shows that proteins associate along preferred pathways, similar to the sliding of a protein along DNA.
    1. Computational and Systems Biology

    Meta-Research: Centralized scientific communities are less likely to generate replicable results

    Valentin Danchev et al.
    Analysis of data on drug-gene interactions suggests that decentralized collaboration will increase the robustness of scientific findings in biomedical research.
    1. Microbiology and Infectious Disease

    Research: A comprehensive and quantitative exploration of thousands of viral genomes

    Gita Mahmoudabadi, Rob Phillips
    A compendium of critical genomic numbers for viruses through the lenses of different viral classification systems.
    1. Epidemiology and Global Health

    Science Forum: Unit of analysis issues in laboratory-based research

    Nick R Parsons et al.
    A simulation study is used to demonstrate how mistakes in identifying the experimental unit and the unit of analysis can lead to incorrect analyses and inappropriate inferences when reporting research studies.
    1. Human Biology and Medicine
    2. Neuroscience

    Point of View: Predictive regulation and human design

    Peter Sterling
    Why does the human regulatory system, which evolution tuned for small satisfactions, now constantly demand 'more'?
    1. Cell Biology
    2. Computational and Systems Biology

    Science Forum: The Human Cell Atlas

    Aviv Regev et al.
    Advances in techniques for analysing single cells and tissues have inspired an international effort to create comprehensive reference maps of all human cells - the fundamental units of life - as a basis for both understanding human health and diagnosing, monitoring and treating disease.
  1. Research: United States National Postdoc Survey results and the interaction of gender, career choice and mentor impact

    Sean C McConnell et al.
    The quality of mentoring received while a postdoc influences career choice irrespective of field, gender, or ethnicity, according to a 7,603-respondent postdoc survey.
    1. Ecology
    2. Evolutionary Biology

    The Natural History of Model Organisms: C. elegans outside the Petri dish

    Lise Frézal, Marie-Anne Félix
    To leverage the tools, resources and knowledge that exist for C. elegans so that we can study ecology, evolution and other aspects of biology, we need to understand the natural history of this important model organism.
    1. Human Biology and Medicine

    Meta-Research: Gender variations in citation distributions in medicine are very small and due to self-citation and journal prestige

    Jens Peter Andersen et al.
    In studies of gender disparities in academia, increased focus is required on within-group variability and between-group overlap of distributions when interpreting and reporting results.
    1. Neuroscience

    Integrative and distinctive coding of visual and conceptual object features in the ventral visual stream

    Chris B Martin et al.
    Perirhinal cortex, a brain structure located in the medial temporal lobe, uniquely supports the integration of visual and conceptual object information.

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