14 results found
    1. Neuroscience

    Midbrain dopaminergic inputs gate amygdala intercalated cell clusters by distinct and cooperative mechanisms in male mice

    Ayla Aksoy-Aksel et al.
    Dopaminergic input shapes activity of specialized amygdala inhibitory cell clusters by ionotropic and metabotropic mechanisms that may enable their selection during distinct fear-related behavioral states.
    1. Computational and Systems Biology
    2. Neuroscience

    Action detection using a neural network elucidates the genetics of mouse grooming behavior

    Brian Q Geuther et al.
    A machine learning method for action detection is developed and applied toward mouse grooming behavior.
    1. Stem Cells and Regenerative Medicine

    A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids

    Henrik Renner et al.
    Automated liquid handling, whole mount staining, and clearing allow unbiased 3D quantitation of cell markers in human neural organoids with diameters of up to 1 mm at the single-cell level.
    1. Neuroscience

    Cellular taxonomy and spatial organization of the murine ventral posterior hypothalamus

    Laura E Mickelsen et al.
    Single cell RNA–sequencing and neuroanatomical methods reveal unexpected molecular diversity and highly segregated spatial organization of neuronal cell types within the mouse ventral posterior hypothalamus, including the mammillary nuclei.
    1. Neuroscience

    Relaxation of synaptic inhibitory events as a compensatory mechanism in fetal SOD spinal motor networks

    Pascal Branchereau et al.
    Electrophysiological and simulation approaches show that a chloride-related longer relaxation of the inhibitory synaptic events partially compensates the early defect in the chloride homeostasis detected in fetal SOD spinal motoneurons.
    1. Neuroscience

    Motor cortex can directly drive the globus pallidus neurons in a projection neuron type-dependent manner in the rat

    Fuyuki Karube et al.
    Globus pallidus neurons projecting to the striatum are preferentially activated by direct glutamatergic innervation from the motor cortex.
    1. Neuroscience

    Generality and opponency of rostromedial tegmental (RMTg) roles in valence processing

    Hao Li et al.
    Rostromedial tegmental neurons encode motivational valence and opponent responses across a wide range of affective stimulus modalities, while also driving dopamine inhibition and conditioned place aversion to aversive stimuli.
    1. Neuroscience

    Differential inputs to striatal cholinergic and parvalbumin interneurons imply functional distinctions

    Jason R Klug et al.
    A brain-wide mapping of the direct inputs to striatal cholinergic and parvalbumin interneurons reveals connectivity differences and implies their distinct roles in regulating striatal function.
    1. Neuroscience

    miR-9 regulates basal ganglia-dependent developmental vocal learning and adult vocal performance in songbirds

    Zhimin Shi et al.
    Gene manipulation combined with behavior analysis reveals a role of miR-9 in modulating basal-ganglia-dependent developmental vocal learning and adult vocal performance via regulating the FOXP1/FOXP2 gene network and dopamine signaling in songbirds.
    1. Neuroscience

    Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus

    Xiang-Shan Yuan et al.
    Rostral and central striatum controls slow-wave sleep during active phase in mice.

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