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1 result found
Neuroscience
Antisense, but not sense, repeat expanded RNAs activate PKR/eIF2α-dependent ISR in
C9ORF72
FTD/ALS
Janani Parameswaran, Nancy Zhang ... Jie Jiang
C9ORF72 antisense repeat expanded RNAs activate PKR/eIF2α dependent integrated stress response and cause neuronal toxicity independent of DPR proteins.
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