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    1. Neuroscience

    Drosophila mushroom bodies integrate hunger and satiety signals to control innate food-seeking behavior

    Chang-Hui Tsao et al.
    Mushroom bodies are a hunger and satiety integrative center that controls food-seeking behavior in Drosophila..
    1. Neuroscience

    optoPAD, a closed-loop optogenetics system to study the circuit basis of feeding behaviors

    José-Maria Moreira et al.
    The optoPAD system combines real-time behavioral analysis with optogenetic manipulations to study how animals adapt to dynamic gustatory environments and to identify the circuit basis of feeding.
    1. Neuroscience

    Closed-loop optogenetic activation of peripheral or central neurons modulates feeding in freely moving Drosophila

    Pierre-Yves Musso et al.
    The Sip-Triggered Optogenetic Behavior Enclosure (STROBE) produces robust behaviors via activation of peripheral or central neurons in the fly, and mimics key features of feeding driven by chemical taste ligands.
    1. Neuroscience

    Convergence of monosynaptic and polysynaptic sensory paths onto common motor outputs in a Drosophila feeding connectome

    Anton Miroschnikow et al.
    A parallel neuronal network architecture ensures control of basic feeding reflex circuits via integration of crossmodal sensory information to filter multiple biological events and enhance meaningful behavioral choice.
    1. Neuroscience

    The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice

    Xiang-Chun Ju et al.
    Introducing a hominoid-specific gene into mice induces cortical folding.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    N-glycosylation in the protease domain of trypsin-like serine proteases mediates calnexin-assisted protein folding

    Hao Wang et al.
    N-glycans commonly present in the protease domains are required for calnexin-mediated protein folding and intracellular trafficking.
    1. Cell Biology

    Ubiquitin-dependent folding of the Wnt signaling coreceptor LRP6

    Elsa Perrody et al.
    A novel folding machinery assists transmembrane proteins from the cytosolic side of the endoplasmic reticulum.
    1. Neuroscience

    Direct modulation of GFAP-expressing glia in the arcuate nucleus bi-directionally regulates feeding

    Naiyan Chen et al.
    Glial fibrillary acidic protein-expressing glia in the arcuate nucleus of the hypothalamus modulate feeding in mice.
    1. Neuroscience

    Motor control of Drosophila feeding behavior

    Olivia Schwarz et al.
    The neuroanatomical and functional analysis of genetically-identified motoneurons controlling all major steps of Drosophila proboscis extension provides new insights into the architecture of a motor circuitry controlling a reaching-like behavior.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Protein-mediated RNA folding governs sequence-specific interactions between rotavirus genome segments

    Alexander Borodavka et al.
    In rotaviruses, the selective packaging of eleven distinct genomic RNA segments requires virus-encoded protein NSP2 to alter the RNA structures, facilitating their interactions with each other.