18 results found
    1. Neuroscience

    The recovery of standing and locomotion after spinal cord injury does not require task-specific training

    Jonathan Harnie et al.
    Restoring locomotion after complete spinal cord injury does not require locomotor training, only the return of sufficient excitability within neurons of the spinal cord.
    1. Microbiology and Infectious Disease
    2. Genetics and Genomics

    Dissection of the in vitro developmental program of Hammondia hammondi reveals a link between stress sensitivity and life cycle flexibility in Toxoplasma gondii

    Sarah L Sokol et al.
    A derived stress response trait may have contributed to the emergence of a globally dominant and promiscuous parasite.
    1. Cell Biology
    2. Evolutionary Biology

    TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants

    Michael Sulak et al.
    Elephants escaped enhanced cancer susceptibility by evolving more master tumor suppressor genes.
    1. Microbiology and Infectious Disease

    Reciprocal virulence and resistance polymorphism in the relationship between Toxoplasma gondii and the house mouse

    Jingtao Lilue et al.
    Mechanisms that enable wild mice to survive infection with strains of the Toxoplasma gondii parasite virulent enough to kill laboratory mice offer an explanation for how these parasites have been able to persist in the mouse population.
    1. Human Biology and Medicine
    2. Neuroscience

    Human hippocampal CA3 damage disrupts both recent and remote episodic memories

    Thomas D Miller et al.
    Human hippocampal cornu ammonis 3 damage impairs both recent and remote autobiographical episodic memory, and disrupts functional integration in medial temporal lobe subsystem regions of the default network.
    1. Developmental Biology
    2. Genetics and Genomics

    A genome-wide resource for the analysis of protein localisation in Drosophila

    Mihail Sarov et al.
    A large-scale transgenic resource enables live imaging, subcellular localisation and interaction proteomics of specific gene products of interest at all stages of Drosophila development.
    1. Neuroscience

    Network-wide abnormalities explain memory variability in hippocampal amnesia

    Georgios PD Argyropoulos et al.
    Hippocampal damage is associated with changes across the extended hippocampal system, and these may explain variability in memory between patients presenting with hippocampal amnesia.
    1. Cell Biology
    2. Human Biology and Medicine

    Peroxisomal lactate dehydrogenase is generated by translational readthrough in mammals

    Fabian Schueren et al.
    Whole-genome in silico screening for stop codon contexts that produce elevated translational readthrough and peroxisome targeting reveals that in mammals, the amount of lactate dehydrogenase in the peroxisome is controlled by translational readthrough.
    1. Ecology
    2. Evolutionary Biology

    Tooth fracture frequency in gray wolves reflects prey availability

    Blaire Van Valkenburgh et al.
    Despite risks of infection and reduced fitness, tooth fracture frequency in gray wolves increases rapidly when prey are scarce because they must consume carcasses more completely.
    1. Ecology
    2. Evolutionary Biology

    The Natural History of Model Organisms: C. elegans outside the Petri dish

    Lise Frézal, Marie-Anne Félix
    To leverage the tools, resources and knowledge that exist for C. elegans so that we can study ecology, evolution and other aspects of biology, we need to understand the natural history of this important model organism.

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