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Human red blood cells from healthy donors display marked biophysical and genetic variation that impacts the growth of Plasmodium falciparum malaria parasites, outside of known disease alleles.

Complete blood count data can increase the accuracy of the diagnosis of severe malaria in children in high transmission settings.

In contrast with earlier conclusions, negative selection has a major role in cancer evolution.

Mathematical models of the build-up and depletion of the hypnozoite reservoir in the liver can inform the design of treatment strategies for preventing Plasmodium vivax relapse infections.

Lower malaria prevalence in females does not appear to be due to lower rates of infection but rather due to faster clearance of asymptomatic infections.

The incorporation of as yet underused local epidemiological data on α-thalassaemia in Southeast Asia within a geostatistical model suggests that the burden of severe α-thalassaemia forms may have been underestimated.

Examining gene expression in the Fulani, an ethnic group relatively protected from malaria, identifies a more transcriptionally reactive response in cells of the innate immune system.

Degenerating motor neurons compensate for energetic deficits by upregulating glycolysis in flies and humans, with increased glucose availability improving locomotor function and lifespan in flies.

Acute myocardial infarction patient-derived endothelial cells display a strong mitochondrial proton coupling with excess ROS production, enhanced glutamine metabolism and a carbon source switch from glucose to glutamine.

A new zebrafish RBC aggregation model is developed to explore the dynamic process and the underlying regulatory mechanisms in blood clot formation.