Susan Martin, Jessica Tyrrell ... Hanieh Yaghootkar
Using genetics, it is possible to uncouple higher adiposity from its adverse metabolic effects and show that some obesity-associated conditions may benefit from treating the metabolic effects alone, whilst others may benefit more from weight loss.
A Sarah Walker, Emma Pritchard ... COVID-19 Infection Survey team
Wide variation in cycle threshold (Ct) values from SARS-CoV-2 RT-PCR tests over calendar time offers the potential for their broader use in public testing programmes as an ‘early-warning’ system for shifts in infectious load and hence transmission.
A comprehensive genome scan of 18,000 multi-ethnic individuals with 3-dimensional facial images highlighted multiple face-associated genetic loci for which regulatory activities in human neural cells were established.
Quorum sensing enables heterogeneous production of autoinducers in microbial populations, suggesting an alternative mechanism to stochastic gene expression in bistable gene-regulatory circuits to control phenotypic heterogeneity.
Andrea S Meseguer, Alice Michel ... Fabien L Condamine
Neotropical outstanding biodiversity emerged from sustained rates of species accumulation over time, although, for some periods, tetrapods were less successful than plants in keeping pace with a changing environment.
Man Yi Yim, Lorenzo A Sadun ... Thibaud Taillefumier
A very large number of place-field maps can be robustly learned by association of external cues with the grid-driven response, however plasticity in the grid-cell inputs renders the place-cell responses volatile.
A compact neural network can form various associative memories that are encoded in a distributed manner, where each neuron stores different components of the memory.