By inhibiting the activation of NF-κB, HIV-1 Vpu exerts much broader immunosuppressive effects than previously anticipated and may be an important determinant of chronic inflammation in HIV-1 infected individuals.

Rats can pre-position the state of their basal ganglia neural networks to adaptively influence their subsequent response to a Go signal.

HIV-1 viral protein u (Vpu) can stimulate novel versions of canonical interactions with the clathrin adaptor AP1 to counteract the host antiviral protein BST2.

AIRE played novel roles in the mitosis process in embryonic stem cells and early embryo cells.

Using GPUs for the costly computations in cryo-EM enables structure determination in mere days on a single workstation.

Addressing the controversy regarding the interpretation of choice probabilities demonstrates that both readout strategy and noise correlations contribute to the link between neural activity and perceptual decisions.

Disrupting extrusion, a process that drives epithelial cell death, leads to increased cell survival, poor barrier function, and enhanced cell invasion and, thereby, promotes tumor initiation and progression.

GDE3 is a transmembrane GPI-specific phospholipase C that sheds the urokinase receptor (uPAR) from the cell surface resulting in loss of uPAR function in breast cancer cells and reduced tumor growth.

H3K23me3 is a RNAi-mediated transgenerationally heritable heterochromatin mark in Caenorhabditis elegans.

Anterior insular cortex activity predicts how well we attend to our bodily signals, while lesions to this brain region disrupt this ability.