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Gab1 is a key downstream effector of PDGF signaling and essential to oligodendrocyte differentiation by linking PDGF signaling with GSK3β/β-catenin module.

Brassinosteroids signal through a pathway involving GSK3-like kinases and the WER-GL3/EGL3-TTG1 transcription factor complex to determine the fate of cells in the root epidermis.

Telomere dysfunction in iPSC-derived type II alveolar epithelial cells causes senescence and gene expression changes including Wnt-related changes that GSK3 inhibition can rescue, providing insight into pulmonary fibrosis pathogenesis.

The kinase GSK-3 regulates cortical neuronal migration and dendritic orientation by phosphorylating key cytoskeletal proteins.

Dkk2, a member of the Dikkopf family of Wnt antagonists, acts as a positive regulator of Wnt signaling during neural crest formation.

A new dynamic mechanistic model explains how the destruction complex negatively regulates Wnt signaling in development and oncogenesis.

Systemic treatment with di-methyl-amino-parthenolide facilitates CNS axon regeneration and functional recovery by reducing the induction of microtubule detyrosination by established regenerative therapies.

Small molecule inhibition of stem cell differentiation in vitro provides novel insight into how DYRK1A loss disrupts human nervous system development.

CRMP4 is a new actor in the guidance cue Semaphorin-3E pathway, crucially involved in the establishment of the fornix, a key axonal tract for memory and emotional control.

Protein kinase A-driven increases in c-MYC protein expression and tumor cell proliferation can be blocked by eIF4A inhibitors, suggesting a potential new treatment option for patients with oncogenic PKA activation.