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    1. Neuroscience

    Causal links between parietal alpha activity and spatial auditory attention

    Yuqi Deng, Robert MG Reinhart ... Barbara G Shinn-Cunningham
    Stimulating one side of parietal cortex using an appropriate frequency of alternating current interferes with attention to a sound stream from a location on the opposite side of a space.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Alpha-satellite RNA transcripts are repressed by centromere–nucleolus associations

    Leah Bury, Brittania Moodie ... Iain M Cheeseman
    Single molecule FISH analysis defines the behavior of centromere-derived alpha-satellite transcripts in intact human cells and reveals a critical role for centromere-nucleolar contacts in repressing alpha-satellite transcription.
    1. Neuroscience

    Modulation of alpha oscillations by attention is predicted by hemispheric asymmetry of subcortical regions

    Tara Ghafari, Cecilia Mazzetti ... Ole Jensen
    Lateral asymmetry of the globus pallidus, caudate nucleus, and thalamus can predict attention-related modulations of posterior alpha oscillations when combining structural MRI with MEG.
    1. Neuroscience

    Decomposing the role of alpha oscillations during brain maturation

    Marius Tröndle, Tzvetan Popov ... Nicolas Langer
    Applying decomposition of oscillatory and aperiodic signal components to developmental EEG data provides a solution for the problems in the investigation of alpha power during brain maturation.
    1. Neuroscience

    Increased theta/alpha synchrony in the habenula-prefrontal network with negative emotional stimuli in human patients

    Yongzhi Huang, Bomin Sun ... Huiling Tan
    Increased theta/alpha band activities within the habenula area and the prefrontal cortex, as well as the increased synchrony between the two structures in the same frequency band can serve as an indicator for negative emotions in humans.
    1. Structural Biology and Molecular Biophysics

    Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation

    Sean W Fanning, Christopher G Mayne ... Geoffrey L Greene
    Two common mutant versions of estrogen receptor alpha achieve constitutive activity and hormone-resistance by preferentially adopting a suite of conformations that expose the coregulator-binding surface.
    1. Neuroscience

    Electrocorticographic dissociation of alpha and beta rhythmic activity in the human sensorimotor system

    Arjen Stolk, Loek Brinkman ... Ivan Toni
    Direct cortical recordings in humans link the spectral structure of local field potentials to inhibition/disinhibition mechanisms coordinating sensorimotor neuronal populations during movement imagery.
    1. Cell Biology
    2. Medicine

    Polymerization of misfolded Z alpha-1 antitrypsin protein lowers CX3CR1 expression in human PBMCs

    Srinu Tumpara, Matthias Ballmaier ... Sabina Janciauskiene
    Finding that circulating Z alpha-1 antitrypsin polymers, a feature of ZZ AAT deficiency, lower the expression of CX3CR1 on peripheral blood mononuclear cells encourages more detailed analyses on different circulating misfolded proteins and their role on immune cell surveillance/function.
    1. Neuroscience

    Brain-derived and in vitro-seeded alpha-synuclein fibrils exhibit distinct biophysical profiles

    Selene Seoyun Lee, Livia Civitelli, Laura Parkkinen
    The in-vitro seeded fibrils are unlikely to be disease-relevant and representative of the diverse alpha-synuclein polymorphs in the brain.
    1. Computational and Systems Biology
    2. Neuroscience

    Stochastic resonance mediates the state-dependent effect of periodic stimulation on cortical alpha oscillations

    Jérémie Lefebvre, Axel Hutt, Flavio Frohlich
    Stochastic resonance, triggered by fluctuations in brain state, is found to determine the outcomes of periodic stimulation and how it interacts with brain oscillations.