19 results found
    1. Neuroscience

    Pedunculopontine glutamatergic neurons control spike patterning in substantia nigra dopaminergic neurons

    Daniel J Galtieri et al.
    Pedunculopontine neurons can evoke burst spiking in substantia nigra dopaminergic neurons without engaging a subtype of glutamate receptor previously thought to be necessary for this spiking mode.
    1. Evolutionary Biology

    The genomes of polyextremophilic cyanidiales contain 1% horizontally transferred genes with diverse adaptive functions

    Alessandro W Rossoni et al.
    Horizontal gene transfer (HGT) analysis in polyextremophile red algae (Cyanidiales) provides explanations for the nonexistence of cumulative effects and eukaryotic pangenomes, and highlights differences between HGT and native genes.
    1. Cancer Biology
    2. Immunology and Inflammation

    Human primed ILCPs support endothelial activation through NF-κB signaling

    Giulia Vanoni et al.
    Circulating human primed innate lymphoid cell precursors have the potential to functionally induce adhesion molecules' expression in endothelial cells and possibly support the immune cells' infiltration into the tumor site.
    1. Evolutionary Biology

    New footprints from Laetoli (Tanzania) provide evidence for marked body size variation in early hominins

    Fidelis T Masao et al.
    Bipedal footprints made 3.66 million years ago provide the clearest available evidence to date of the occurrence of marked body size variation in Australopithecus afarensis..
    1. Evolutionary Biology
    2. Plant Biology

    Ascorbate Biosynthesis: A cross-kingdom history

    Alisdair R Fernie, Takayuki Tohge
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    1. Evolutionary Biology
    2. Plant Biology

    Evolution of alternative biosynthetic pathways for vitamin C following plastid acquisition in photosynthetic eukaryotes

    Glen Wheeler et al.
    Genomic evidence suggests that L-gulonolactone oxidase-the terminal enzyme in vitamin C synthesis, which has been repeatedly lost throughout animal evolution-was lost in plants and other photosynthetic eukaryotes following plastid acquisition.
    1. Cell Biology

    EGF receptor signaling, phosphorylation, ubiquitylation and endocytosis in tumors in vivo

    Itziar Pinilla-Macua et al.
    A small pool of active epidermal growth factor (EGF) receptors, which are capable of ubiquitylation and efficient endocytosis in vivo, is sufficient to support EGF-receptor-dependent tumor growth by signaling primarily through the Ras-MAPK pathway.
    1. Chromosomes and Gene Expression

    Histone H3 threonine 11 phosphorylation by Sch9 and CK2 regulates chronological lifespan by controlling the nutritional stress response

    Seunghee Oh et al.
    Histone H3T11 phosphorylation regulates chronological lifespan by linking nutritional stress-response signals to chromatin.
    1. Genetics and Genomics

    Firefly genomes illuminate parallel origins of bioluminescence in beetles

    Timothy R Fallon et al.
    The first genomic view of beetle luciferase evolution indicates evolutionary independence of luciferase between fireflies and click-beetles, and provide valuable datasets which will accelerate the discovery of new biotechnological tools.
    1. Ecology

    Entomopathogenic nematodes increase predation success by inducing cadaver volatiles that attract healthy herbivores

    Xi Zhang et al.
    By changing the smell of their host, entomopathogenic nematodes attract future hosts and increase their predation success.

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