16 results found
    1. Neuroscience

    Pedunculopontine glutamatergic neurons control spike patterning in substantia nigra dopaminergic neurons

    Daniel J Galtieri et al.
    Pedunculopontine neurons can evoke burst spiking in substantia nigra dopaminergic neurons without engaging a subtype of glutamate receptor previously thought to be necessary for this spiking mode.
    1. Evolutionary Biology
    2. Plant Biology

    Ascorbate Biosynthesis: A cross-kingdom history

    Alisdair R Fernie, Takayuki Tohge
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    1. Evolutionary Biology
    2. Plant Biology

    Evolution of alternative biosynthetic pathways for vitamin C following plastid acquisition in photosynthetic eukaryotes

    Glen Wheeler et al.
    Genomic evidence suggests that L-gulonolactone oxidase-the terminal enzyme in vitamin C synthesis, which has been repeatedly lost throughout animal evolution-was lost in plants and other photosynthetic eukaryotes following plastid acquisition.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy

    Paolo Grumati et al.
    Full length RTN3 homodimerization mediates ER tubules fragmentation and their subsequent delivery to lysosome.
    1. Biochemistry and Chemical Biology

    The ribosomal protein Asc1/RACK1 is required for efficient translation of short mRNAs

    Mary K Thompson et al.
    Asc1/RACK1 promotes the translation of mRNAs associated with the translational closed loop complex, which have short open reading frames and encode proteins required for core metabolic processes.
    1. Ecology

    Entomopathogenic nematodes increase predation success by inducing cadaver volatiles that attract healthy herbivores

    Xi Zhang et al.
    By changing the smell of their host, entomopathogenic nematodes attract future hosts and increase their predation success.
    1. Cell Biology

    Generation of endogenous pH-sensitive EGF receptor and its application in high-throughput screening for proteins involved in clathrin-mediated endocytosis

    Mads Breum Larsen et al.
    CRISPR/Cas9 gene-editing was used to generate a novel endogenous pH-sensitive EGF receptor chimera with the unique utility to study receptor endocytosis in a single-cell and high-throughput experimental formats.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    A common bacterial metabolite elicits prion-based bypass of glucose repression

    David M Garcia et al.
    Activity-guided fractionation identifies the first bacterial metabolite that potently induces a prion in nature.
    1. Genetics and Genomics

    Evidence for loss and reacquisition of alcoholic fermentation in a fructophilic yeast lineage

    Carla Gonçalves et al.
    Comparative genomics coupled with genetic and biochemical studies show that central carbon metabolism in fungi can be remodeled by genes originating from bacteria.
    1. Evolutionary Biology

    The genomes of polyextremophilic cyanidiales contain 1% horizontally transferred genes with diverse adaptive functions

    Alessandro W Rossoni et al.
    Horizontal gene transfer (HGT) analysis in polyextremophile red algae (Cyanidiales) provides explanations for the nonexistence of cumulative effects and eukaryotic pangenomes, and highlights differences between HGT and native genes.

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