Joseph Robert Piechura, Kapil Amarnath, Erin K O'Shea
Cyanobacteria cope with both predictable day/night changes and natural fluctuations in light during the day by adjusting the expression dynamics of circadian-clock-controlled genes via a network of transcriptional regulators.
Integration of automatic behavioral tracking with brain molecular profiling reveals the role of gene regulatory network plasticity in the regulation of behavioral phenotypes.
Maria Gutierrez-Arcelus, Tuuli Lappalainen ... Emmanouil T Dermitzakis
Detailed analysis of umbilical cord cells shows that the associations between DNA methylation, gene expression and genetic variation are complex and context-dependent.
Aynur Kaya-Çopur, Fabio Marchiano ... Frank Schnorrer
Muscle fiber growth during development is controlled by the Hippo pathway that links the assembly state of the contractile sarcomeres with the transcriptional state of the sarcomeric genes.
Christopher D Todd, Özgen Deniz ... Miguel R Branco
Genetic and epigenetic editing experiments establish causal links between transposon-derived enhancers and gene regulation in mouse embryonic and extraembryonic lineages.
For mRNA decapping by enhancing DCP2's mRNA-binding affinity and regulating distinct biological processes through DCP1a and DCP1b, human DCP1 is essential.
Helen M Tauc, Imilce A Rodriguez-Fernandez ... Heinrich Jasper
Global, multi-angled genetic analyses identified an age-associated loss of stem cell lineage fidelity that was linked to changes in polycomb regulation in the Drosophila intestinal epithelium.
Sequential expression of two transcription factors that bind to five- and ten-base female-specific cis-acting elements, respectively, promotes differentiation of Plasmodium female gametocytes.