A new approach measures the respective participations of elementary cell behaviors – such as cell division, intercalation, shape change and death – in the shaping of animal tissues.

Metabotropic glutamate receptors modulate impulse control by the subthalamic nucleus, dissociating trait impulsivity from basal ganglia motor function.

A phosphorylation circuitry balancing among kinase, transcription factor, transcription repressor, and phosphatase in response against host immunity during M. oryzae–rice interaction.

Development of a robust Th1 response to infection against an intracellular parasite requires T-cell intrinsic MyD88 signaling, mostly through the upstream IL-18 receptor, for the induction of genes involved in proliferation, cytokine production and migration.

Analysis of protein interfaces suggests cotranslational assembly can be an adaptive process, likely serving to minimise non-specific interactions with other proteins in the cell.

Osteoblast dedifferentiation and migration are injury responses that are differentially regulated and independent of regenerative bone formation.

Analysis of inositol pyrophosphate dynamics upon inorganic phosphate (P_i) starvation identifies 1,5-IP₈ as the inositol pyrophosphate isomer signaling P_i sufficiency to the SPX domain of Pho81 that controls the transcriptional P_i starvation program.

Combined simulations and electrophysiological experiments show that the CLC channels and exchangers form physically distinct and evolutionarily conserved pathways through which Cl^- and H⁺ ions move when crossing biological membranes.

A multidimensional chemical mapping strategy enables confident determination of the structures of non-coding RNAs at 1-nm resolution, including previously intractable riboswitch and human regulon states.

Transcriptomic, enzyme activity, and flux data demonstrate that metabolic scaling, the inverse correlation between body size and metabolic rate per gram of tissue, is a conserved phenomenon that occurs at multiple physiological levels and in multiple tissues.