Novel modelling strategies can integrate the dynamics of processes regulating the intestinal epithelium at multiple scales in homeostasis and following perturbations to provide unprecedented insights into the biology of the epithelium and support the development of safer novel drug candidates.

Anarchic, cycling piwi-1+ embryonic cells gives rise to neoblasts, pluripotent stemcells required for development of all organ systems during S. mediterranea embryogenesis, as well as the maintenance andregeneration of tissues during adulthood.

The ability to adjust body size in response to diet is greater in Drosophila females than males because of a sex difference in the nutrient-dependent regulation of the insulin pathway.

A large collaborative project combined many different researchers' forecasts of COVID-19 across Europe, making predictions used in policy more reliable.

Dual resin casting of multiple lumenized systems followed by microCT allows visualization, digitalization, and quantification of architectural parameters defining the vascular and biliary systems in liver revealing new phenotypes.

The first genomic view of beetle luciferase evolution indicates evolutionary independence of luciferase between fireflies and click-beetles, and provide valuable datasets which will accelerate the discovery of new biotechnological tools.

An in vivo electrophysiology approach identifies an incretin-like effect in Drosophila insulin-producing cells, highlighting key circuit dynamics which govern glucose homeostasis via conserved mechanisms.

aLENS implements new parallel methods to resolve cytoskeletal assembly dynamics with high stability, physical consistency, and scalability.

Cryo-electron microscopy reveals previously undescribed structural features of choanoflagellate flagella and provides new insights into flagellar evolution.

Genome sequence analysis of Mycobacterium tuberculosis clinical isolates and subsequent validation in laboratory and animal infection models identify previously unrecognized genetic mutations in DNA repair genes that contribute to the development of drug resistance.