Making human stem cells express certain transcription factors can convert them into cells that are similar to ovarian granulosa cells, and perform several important functions of the ovary.

FOXL2 maintenance of ovarian identity is not solely due to a simple direct repression of Sox9 but to the mobilization of estrogen signalling by FOXL2.

PRMT5 participates in ovarian granulosa cell lineage maintenance by regulating Wt1 IRES-dependent translation.

Depletion of the TGFβ signal-transducer, SMAD4, in granulosa cells of growing follicles reduces the number of filopodia, termed transzonal projections, that stably attach to and mediate communication with the oocyte.

A phosphorylation of receptor interacting RIPK3 switches its pro-necroptosis function to apoptosis that promotes luteal regression which induced by Prostaglandin F2alpha.

The vertebrate testis-determining gene, Sox9, also controls adult testis maintenance in mammals, acting redundantly with its paralog Sox8.

A survey of the transcriptomic landscape of the mouse ovary at the single-cell level reveals both the cellular complexity of this organs and the dynamic nature of the cellular states that accompany estrous cycling.

Single-cell transcriptomics of the zebrafish ovary identifies both major and minor cell types and provides a valuable resource for researchers interested in reproductive biology, stem cell biology, and aquatic toxicology.

Humans with mutations in the AIRE gene exhibit common autoantibodies targeting ovarian and intestinal antigens, including intestinal dysfunction-associated antibodies to enteroendocrine transcription factor RFX6.