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    1. Epidemiology and Global Health

    Direct and indirect mortality impacts of the COVID-19 pandemic in the United States, March 1, 2020 to January 1, 2022

    Wha-Eum Lee, Sang Woo Park ... Cécile Viboud
    The overall mortality consequences of the COVID-19 pandemic in the United States are predominantly attributable to the direct impact of SARS-CoV-2 infection but there are substantial indirect effects among children and young adults, and in mortality from accidents, homicides, and overdoses.
    1. Epidemiology and Global Health

    3D virtual histopathology of cardiac tissue from Covid-19 patients based on phase-contrast X-ray tomography

    Marius Reichardt, Patrick Moller Jensen ... Tim Salditt
    X-ray phase-contrast tomography reveals pathology of capillaries in heart tissue from patients who succumbed to Covid-19, as well as alterations in the three-dimensional cardiac tissue structure.
    1. Epidemiology and Global Health
    2. Medicine

    Pan-Canadian survey on the impact of the COVID-19 pandemic on cervical cancer screening and management: cross-sectional survey of healthcare professionals

    Mariam El-Zein, Rami Ali ... Survey Study Group
    Decline in cervical cancer screening and challenges faced by healthcare professionals and patients when the pandemic was declared emphasize the importance of implementing human papillomavirus (HPV) primary screening, HPV self-sampling, and telemedicine to continue cervical cancer screening and care.
    1. Medicine
    2. Microbiology and Infectious Disease

    Early prediction of level-of-care requirements in patients with COVID-19

    Boran Hao, Shahabeddin Sotudian ... Ioannis Ch Paschalidis
    Using data for 2566 COVID-19 patients from five hospitals, models are developed to predict for each patient hospitalization and critical care needs, based on demographics, comorbidities, medications, and laboratory findings.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Superspreaders drive the largest outbreaks of hospital onset COVID-19 infections

    Christopher JR Illingworth, William L Hamilton ... M Estée Török
    Outbreaks of SARS-CoV-2 transmission in a hospital environment show evidence of superspreading, with 80% of infections caused by 21% of infected individuals.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    The unmitigated profile of COVID-19 infectiousness

    Ron Sender, Yinon Bar-On ... Ron Milo
    In the absence of COVID-19 mitigation measures, SARS-CoV-2 remains infectious for longer than previously estimated.
    1. Medicine

    Meta-Research: COVID-19 medical papers have fewer women first authors than expected

    Jens Peter Andersen, Mathias Wullum Nielsen ... Reshma Jagsi
    Lockdowns in the United States caused by the COVID-19 pandemic appear related to a decrease in the number of women publishing research papers, especially as first authors.
    1. Epidemiology and Global Health

    Projected long-term effects of colorectal cancer screening disruptions following the COVID-19 pandemic

    Pedro Nascimento de Lima, Rosita van den Puttelaar ... Carolyn M Rutter
    Unequal recovery in colorectal cancer screening following the COVID-19 pandemic can widen disparities in colorectal cancer outcomes.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Rapid feedback on hospital onset SARS-CoV-2 infections combining epidemiological and sequencing data

    Oliver Stirrup, Joseph Hughes ... Judith Breuer
    Epidemiological and viral sequence data can be combined to provide standardised feedback on cases of hospital onset COVID-19 infection that would be useful for infection prevention and control.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Early postmortem mapping of SARS-CoV-2 RNA in patients with COVID-19 and the correlation with tissue damage

    Stefanie Deinhardt-Emmer, Daniel Wittschieber ... Gita Mall
    Early postmortem autopsy of COVID-19 patients shows high viral loads and damage of the lung, although extrapulmonary cells demonstrate no injury, they contribute to inflammation, hyper-coagulation, and multiple organ dysfunction.