Voice your concerns about research culture and research communication: Have your say in our 7th annual survey.
366 results found
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    Co-regulation and function of FOXM1/RHNO1 bidirectional genes in cancer

    Carter J Barger et al.
    FOXM1 is co-expressed with its bidirectional gene partner RHNO1, and the two genes promote DNA repair, cell growth and survival, and chemotherapy resistance in ovarian cancer.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    A spontaneous genetically induced epiallele at a retrotransposon shapes host genome function

    Tessa M Bertozzi et al.
    A retrotransposon-derived recombination event in inbred mice gives rise to an epiallele and tissue-specific phenotypes.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The cis-regulatory effects of modern human-specific variants

    Carly V Weiss et al.
    A genome-wide catalog of the regulatory effects of variants that separate modern humans from archaic humans.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation

    Emma Carley et al.
    Forces stemming from cell-matrix adhesions, but not cell-cell adhesions, are directly transmitted to the nuclear lamina to regulate epidermal cell fate.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Stress resets ancestral heritable small RNA responses

    Leah Houri-Zeevi et al.
    Various types of stress reset heritable small RNA responses through the function of the p38 MAPK pathway, the transcription factor SKN-1/Nrf2, and the MET-2/SETDB1 putative histone methyltransferase.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    A KDM5–Prospero transcriptional axis functions during early neurodevelopment to regulate mushroom body formation

    Hayden AM Hatch et al.
    The histone demethylase KDM5 functions in concert with the transcription factor Prospero to regulate a gene expression program that is required for mushroom body neuroanatomical development.
    1. Chromosomes and Gene Expression

    Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones

    Nina Kirstein et al.
    Replication origins are established throughout the genome with the exception of transcribed genes, and the local chromatin composition likely modulates the density of ORC and MCM as well as origin activation.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Inducible mechanisms of disease tolerance provide an alternative strategy of acquired immunity to malaria

    Wiebke Nahrendorf et al.
    Malaria remodels the spleen to imprint tolerance and reduce pathology in subsequent infections.
    1. Genetics and Genomics

    Age-related changes in polycomb gene regulation disrupt lineage fidelity in intestinal stem cells

    Helen M Tauc et al.
    Global, multi-angled genetic analyses identified an age-associated loss of stem cell lineage fidelity that was linked to changes in polycomb regulation in the Drosophila intestinal epithelium.
    1. Cell Biology
    2. Developmental Biology

    TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation

    Xiaochen Fan et al.
    Network propagation connects TWIST1 with epigenetic regulators CHD7, CHD8, and WHSC1, which collectively promote the bias toward neural crest while suppressing neural stem cell programmes, and subsequently enhance ectomesenchyme potential.

Refine your results by:

Type
Research categories