Interferon lambda 4, a protein part of the innate immune response, drives major amino acids selection in patients chronically infected with hepatitis C virus.

A novel zinc finger transcription factor regulates expression of multiple genes in late stage thymocytes and recent thymic emigrants to promote formation of the naïve T cell compartment.

Structural and biochemical studies indicate that AAA+ ATPase employ a general mechanism to translocate a variety of substrates, including extended polypeptides, hairpins, crosslinked chains, and chains conjugated to other molecules.

Inhibitory interneuron activity is dynamically modulated in new environments while individual interneurons show consistent levels of activity modulation across multiple environments, suggesting functional specialization of inhibitory subnetworks.

Experimental and computational approaches reveal how ligand binding is coupled to voltage sensing in a HCN channels.

A novel automated behavior analysis method for Hydra identifies pre-defined and new behavior types, and reveals a stable behavior repertoire.

Human Neocortical Neurosolver is a new user-friendly software tool for researchers to develop and test hypotheses on cellular/circuit origins of human MEG/EEG signals using a biophysical model.

Mice that successfully avoid developing tinnitus despite exposure to excessive noise show spontaneous recovery of KCNQ2/3 potassium channel activity associated with a reduction in HCN channel activity in auditory brainstem neurons.

NEIL DNA glycosylases are required to counteract oxidative base damages within the mitochondrial genome to safeguard neural crest cell differentiation.

HCN2 channels in the ventral tegmental area play an important role in the pathophysiology of chronic mild stress-induced behavioral deficits.