A naturally acquired human monoclonal antibody recognizes proteins expressed at different stages of the Plasmodium falciparum life cycle through affinity-matured homotypic interactions with glutamate-rich repeats.

Single-molecule localization imaging shows that the Nipah virus fusion protein forms nanoscale clusters on cell and viral membranes that favor membrane fusion activation.

MD-simulations reveal low- to high-affinity conformational shift of orthosteric site in the nicotinic acetylcholine receptor, offering insight into agonist roles in activation dynamics, and highlighting the utility of agonist efficiency.