G-actin binding controls the susceptibility of MRTF-A to phosphorylation, which works in concert with multiple NES elements to regulate MRTF-A subcellular localisation and activity.
Building on previous work (Bai et al., 2013), we describe an algorithm that allows cryo-EM structure determination to near-atomic resolution for protein complexes as small as 170 kDa.
Building on previous work (Diao et al., 2012), we show that the mechanism by which complexin suppresses spontaneous fusion is distinct from the mechanism by which it synchronizes Ca2+-triggered fusion.
Hippocampome.org is an online resource that provides free human- and machine-readable access to the comprehensive property-based classification of hippocampal neurons from 14,000 pieces of published experimental evidence.
In May 2015, we started to encourage our editors and reviewers to use Publons, and there has been healthy interest in this service, with more than 500 peer reviews for eLife now recorded.
