21 results found
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structure of the Helicobacter pylori Cag type IV secretion system

    Jeong Min Chung et al.
    The Helicobacter pylori Cag T4SS has unique structural features, including unexpected symmetry mismatch between sub-complexes, with implications for protein secretion.
    1. Structural Biology and Molecular Biophysics
    2. Chromosomes and Gene Expression

    Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending

    Aleksandra Bebel et al.
    DNA-bound crystal structures of an essential Xer site-specific recombinase from the bacterium Helicobacter pylori reveal how large conformational changes initiate the untangling of chromosomes upon cell division.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition

    Wenyang Chen et al.
    Genetic, structural, and biochemical analyses of IS607-family transposons shows that the DNA translocation reaction proceeds very differently from other reactions promoted by serine recombinases.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    A genetic selection reveals functional metastable structures embedded in a toxin-encoding mRNA

    Sara Masachis et al.
    A genetic selection of toxicity suppressors coupled to high-throughput sequencing has captured metastable RNA structures that co-transcriptionally inhibit the translation of a bacterial toxin.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia

    F Esra Demircioglu et al.
    High resolution structures of the essential human AAA+ ATPase TorsinA and its disease mutant in complex with an activator reveal details of the interaction that will guide drug design and further functional characterization.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Mycobacterium tuberculosis induces decelerated bioenergetic metabolism in human macrophages

    Bridgette M Cumming et al.
    Quantifiable bioenergetic parameters, determined from extracellular flux analyses, are distinct between macrophages infected with Mycobacteriumtuberculosis or vaccine strain M. bovis BCG, enabling assessment of future vaccine and drug efficacy.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Bacterial flagellar capping proteins adopt diverse oligomeric states

    Sandra Postel et al.
    The first high-resolution structure of a bacterial flagellar cap protein, FliD, reveals new insights into the assembly of bacterial flagella.
    1. Epidemiology and Global Health

    Effects of water, sanitation, handwashing, and nutritional interventions on telomere length among children in a cluster-randomized controlled trial in rural Bangladesh

    Audrie Lin et al.
    In a randomized controlled trial in rural Bangladesh, an intensive, combined water, sanitation, handwashing, and nutrition intervention delivered to compounds of newborn children increased telomere length attrition during their first year of life.
    1. Microbiology and Infectious Disease

    Neighbor predation linked to natural competence fosters the transfer of large genomic regions in Vibrio cholerae

    Noémie Matthey et al.
    Whole-genome sequencing reveals the remarkable extent of horizontally moving genetic material in naturally competent Vibrio cholerae after a prey-killing DNA acquisition process.

Refine your results by:

Type
Research categories