Elucidating the molecular mechanism by which the Hippo signaling effector Yorkie (Yki) functions as a transcriptional coactivator in growth control reveals the importance of a histone-modifying enzyme for this process.

The zinc finger protein Nerfin-1 represses the transcriptional output of Hippo signaling in cell competition by binding to the TEA DNA-binding domain of Scalloped.

The cell junction-associated protein Amotl2a controls tissue size in the zebrafish lateral line primordium by limiting the activity of the Hippo effector Yap1 and the Wnt effector Lef1.

The Brahma chromatin remodelling complex interacts with the Hippo signalling pathway to regulate the proliferation and differentiation of stem cells in the Drosophila midgut.

The Hippo signaling restricts the number of SHF cardiomyocytes in the venous pole by negatively regulating Bmp-Smad signaling in the cells of lateral plate mesoderm.

The F-box protein Fbxl7 is a direct effector of the protocadherin Fat and functions in downstream pathways that regulate tissue shape and size.

The transcriptional regulator YAP directs the specification and differentiation of stem cells that give rise to salivary gland ductal epithelium.

The scaffold protein SAV1 counteracts PP2A to activate Hippo kinases.

A contractile structural protein of the membrane-associated cytoskeleton is a Hippo signaling component that works through the regulation of non-muscle myosin activity in Drosophila.

HIPPO signaling antagonizes the apical domain of polarized cells, driving cell internalization, regulated gene expression, and cell fate change during formation of pluripotent stem cell progenitors in the mouse embryo.