801 results found
    1. Neuroscience

    Spatial tuning and brain state account for dorsal hippocampal CA1 activity in a non-spatial learning task

    Kevin Q Shan et al.
    Recordings in freely-moving rats show that hippocampal dorsal CA1 pyramidal cells signal only spatial information, even in a non-spatial task such as trace eyeblink conditioning.
    1. Neuroscience

    CA2 neuronal activity controls hippocampal low gamma and ripple oscillations

    Georgia M Alexander et al.
    Hippocampal area CA2 controls low gamma and ripple oscillations, brain waves known to be impaired in schizophrenia, implicating this important brain region in cognition.
    1. Neuroscience

    Experience-dependent shaping of hippocampal CA1 intracellular activity in novel and familiar environments

    Jeremy D Cohen et al.
    Comparison of the intracellular activity of hippocampal neurons in novel and familiar environments reveals experience-dependent changes in inputs underlying the formation of stable representations of space.
    1. Computational and Systems Biology
    2. Neuroscience

    Interneuronal mechanisms of hippocampal theta oscillations in a full-scale model of the rodent CA1 circuit

    Marianne J Bezaire et al.
    Spontaneous theta oscillations and interneuron-specific phase preferences emerge spontaneously in a full-scale model of the isolated hippocampal CA1 subfield, corroborating and extending recent experimental findings.
    1. Neuroscience

    Dendritic Na+ spikes enable cortical input to drive action potential output from hippocampal CA2 pyramidal neurons

    Qian Sun et al.
    In the hippocampus, dendritic Na + spikes are required for signals from the entorhinal cortex to drive action potentials in CA2-but not CA1 or CA3-pyramidal neurons.
    1. Neuroscience

    Dynamic control of hippocampal spatial coding resolution by local visual cues

    Romain Bourboulou et al.
    Hippocampal spatial coding resolution can quickly adapt to local visual cues within a given environment.
    1. Neuroscience

    CA1 cell activity sequences emerge after reorganization of network correlation structure during associative learning

    Mehrab N Modi et al.
    As mice learn to associate events separated in time, neurons within the CA1 region of the hippocampus progressively reorganize their firing patterns, leading to a relay of cellular activity that bridges the two events.
    1. Neuroscience

    Sub-second dynamics of theta-gamma coupling in hippocampal CA1

    Lu Zhang et al.
    A combination of signal processing and machine learning form a new approach to classify oscillatory coupling in single cycles without averaging over time and to capture cycle-by-cycle changes in coupling.
    1. Neuroscience

    Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1

    Robbert Havekes et al.
    The loss of neuronal connectivity in a brain region called the hippocampus significantly contributes to the cognitive impairments associated with sleep deprivation.
    1. Neuroscience

    Plasticity-dependent, full detonation at hippocampal mossy fiber–CA3 pyramidal neuron synapses

    Nicholas P Vyleta et al.
    Activity-dependent enhancement of transmitter release makes the hippocampal mossy fiber synapse a full detonator in rats.

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