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    1. Immunology and Inflammation

    The RNA binding protein IMP3 facilitates tumor immune escape by downregulating the stress-induced ligands ULPB2 and MICB

    Dominik Schmiedel et al.
    The well-established oncogene IMP3 impairs the interaction between cancer cells and the immune system.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Optimization-by-design of hepatotropic lipid nanoparticles targeting the sodium-taurocholate cotransporting polypeptide

    Dominik Witzigmann et al.
    The combination of in vitro investigations, the zebrafish screening model and rodent experiments offered a unique approach to optimizing nanoparticles modified with Hepatitis B virus-derived peptides to specifically target hepatocytes.
    1. Developmental Biology

    VEGF-C promotes the development of lymphatics in bone and bone loss

    Devon Hominick et al.
    Mice that overexpress VEGF-C in bone display a phenotype that resembles Gorham-Stout disease.
    1. Evolutionary Biology

    Paleontology: These feet were made for walking

    William L Jungers
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    1. Evolutionary Biology

    Human Evolution: The many mysteries of Homo naledi

    Chris Stringer
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    1. Evolutionary Biology

    Human Evolution: New opportunities rising

    Jessica C Thompson
    More fossil specimens and an eagerly awaited age for Homo naledi raise new questions and open new opportunities for paleoanthropologists.
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    1. Evolutionary Biology

    New fossil remains of Homo naledi from the Lesedi Chamber, South Africa

    John Hawks et al.
    The discovery of new skeletal remains of Homo naledi in the Lesedi Chamber, South Africa, adds more evidence to our understanding of the morphology and behavior of this recently discovered species.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    A new family of cell surface located purine transporters in Microsporidia and related fungal endoparasites

    Peter Major et al.
    Transporters shared by fungal intracellular parasites provide new insights into the evolution of nucleotide and energy parasitism.
    1. Ecology
    2. Evolutionary Biology

    The African ape-like foot of Ardipithecus ramidus and its implications for the origin of bipedalism

    Thomas Cody Prang
    The most recent common ancestor of humans, chimpanzees, and bonobos possessed a foot adapted to terrestrial quadrupedalism and climbing.
    1. Evolutionary Biology
    2. Neuroscience

    Quantitative uniqueness of human brain evolution revealed through phylogenetic comparative analysis

    Ian F Miller et al.
    The exceptionally large size of the human brain is the result of accelerating evolution towards larger brains in hominins, but is not the product of neocortical expansion.