122 results found
    1. Evolutionary Biology

    Metabolic co-dependence drives the evolutionarily ancient Hydra–Chlorella symbiosis

    Mayuko Hamada, Katja Schröder ... Thomas CG Bosch
    The symbiotic relationship between Hydra and Chlorella is driven by metabolic co-dependence and characterized by changes in the photobiont genome in terms of lack of genes essential in free-living algae.
    1. Cancer Biology
    2. Cell Biology

    Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells

    Natalia Vydra, Patryk Janus ... Wieslawa Widlak
    Heat shock factor 1 is involved in estrogen-induced chromatin remodeling in estrogen receptor-positive breast cancer cells.
    1. Neuroscience

    Comprehensive machine learning analysis of Hydra behavior reveals a stable basal behavioral repertoire

    Shuting Han, Ekaterina Taralova ... Rafael Yuste
    A novel automated behavior analysis method for Hydra identifies pre-defined and new behavior types, and reveals a stable behavior repertoire.
    1. Neuroscience

    Multiple neuronal networks coordinate Hydra mechanosensory behavior

    Krishna N Badhiwala, Abby S Primack ... Jacob T Robinson
    Despite lacking traditional ganglia or centralization, the Hydra nervous system computes sensorimotor responses via localized neuron ensembles.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Generic injuries are sufficient to induce ectopic Wnt organizers in Hydra

    Jack F Cazet, Adrienne Cho, Celina E Juliano
    Injuries activate the oral identity-specifying canonical Wnt signaling pathway in Hydra, which can trigger head regeneration in permissive tissue contexts created by the absence of pre-existing organizers.
    1. Developmental Biology
    2. Neuroscience

    A new look at the architecture and dynamics of the Hydra nerve net

    Athina Keramidioti, Sandra Schneid ... Charles N David
    A novel pan-neuronal antibody has revealed the organization of the nerve net controlling all behavior in the simple cnidarian Hydra.
    1. Physics of Living Systems

    Spontaneous body wall contractions stabilize the fluid microenvironment that shapes host–microbe associations

    Janna C Nawroth, Christoph Giez ... Thomas CG Bosch
    Spontaneous contractions allow shedding of the fluid boundary layer and thereby stabilize microbiota.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Mapping single-cell atlases throughout Metazoa unravels cell type evolution

    Alexander J Tarashansky, Jacob M Musser ... Bo Wang
    Mapping single-cell atlases throughout Metazoa systematically characterizes cell type diversity and the evolution of their associated gene expression programs.
    1. Chromosomes and Gene Expression

    Translation affects mRNA stability in a codon-dependent manner in human cells

    Qiushuang Wu, Santiago Gerardo Medina ... Ariel Alejandro Bazzini
    Genomic-profiles and reporters reveal that the three-nucleotide ‘words’ read by the ribosome, codons, have a strong effect on mRNA stability, impacting the homeostatic mRNA and protein levels in human cells.

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