A novel automated behavior analysis method for Hydra identifies pre-defined and new behavior types, and reveals a stable behavior repertoire.

A novel pan-neuronal antibody has revealed the organization of the nerve net controlling all behavior in the simple cnidarian Hydra.

Injuries activate the oral identity-specifying canonical Wnt signaling pathway in Hydra, which can trigger head regeneration in permissive tissue contexts created by the absence of pre-existing organizers.

Despite lacking traditional ganglia or centralization, the Hydra nervous system computes sensorimotor responses via localized neuron ensembles.

Spontaneous contractions allow shedding of the fluid boundary layer and thereby stabilize microbiota.

Expression patterns and biophysical properties of acid-sensing ion channels in numerous bilaterian animals offer insight into the deployment of ion channels by the evolving nervous system in complex animals.

The symbiotic relationship between Hydra and Chlorella is driven by metabolic co-dependence and characterized by changes in the photobiont genome in terms of lack of genes essential in free-living algae.

The identification of 31 neuropeptide GPCRs in the sea anemone Nematostella vectensis provides a rich resource to study peptidergic signaling in cnidarians and suggests that cnidarian and bilaterian peptidergic systems diversified independent from each other from a few ancestral systems.

Identification of a two-tier functional redundancy to combat proteostasis imbalance induced due to tRNA expansion and oxidative stress in multicellular animals.