11,213 results found
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    An updated phylogeny of the Alphaproteobacteria reveals that the parasitic Rickettsiales and Holosporales have independent origins

    Sergio A Muñoz-Gómez et al.
    Diverse sophisticated phylogenetic analyses update the phylogeny of the Alphaproteobacteria and show that the parasitic Holosporales is a derived group within the Rhodospirillales order which comprises primarily free-living alphaproteobacteria.
    1. Evolutionary Biology

    The age of Homo naledi and associated sediments in the Rising Star Cave, South Africa

    Paul HGM Dirks et al.
    Independent dating techniques have established that the H. naledi fossils are between 236 and 335 thousand years old, indicating that small-brained hominins with relatively primitive body shapes co-existed with our early ancestors in Africa.
    1. Computational and Systems Biology
    2. Plant Biology

    Coordination of robust single cell rhythms in the Arabidopsis circadian clock via spatial waves of gene expression

    Peter D Gould et al.
    Single cell analysis reveals how period differences between cells and cell-to-cell coupling generates the spatial structure of the plant circadian clock.
    1. Neuroscience

    A circuit mechanism for the propagation of waves of muscle contraction in Drosophila

    Akira Fushiki et al.
    Coordinated activation and deactivation of inhibitory neurons triggers sequential muscle contractions that enable fruit fly larvae to propel themselves backwards and forwards.
    1. Cell Biology
    2. Neuroscience

    Neurexin–Neuroligin 1 regulates synaptic morphology and functions via the WAVE regulatory complex in Drosophila neuromuscular junction

    Guanglin Xing et al.
    Neurexin–Neuroligin1 complex positively regulates F-actin assembly through direct interaction with WAVE complex to control normal synaptic growth and electrophysiological function in Drosophila neuromuscular junction.
    1. Developmental Biology
    2. Physics of Living Systems

    The proneural wave in the Drosophila optic lobe is driven by an excitable reaction-diffusion mechanism

    David J Jörg et al.
    A model of signalling pathways interacting with proneural gene expression explains the sequential patterning of the largest visual processing centre in the developing Drosophila brain.
    1. Developmental Biology
    2. Evolutionary Biology

    The mlpt/Ubr3/Svb module comprises an ancient developmental switch for embryonic patterning

    Suparna Ray et al.
    mille-pattes micropeptides have conserved function in insect embryonic patterning together with transcription factor Shaven-baby and ubiquitin ligase Ubr3, except in flies wherein restoring broad embryonic Svb expression restores patterning potency.
    1. Evolutionary Biology

    A biological switching valve evolved in the female of a sex-role reversed cave insect to receive multiple seminal packages

    Kazunori Yoshizawa et al.
    The discovery of a biological switching valve provides an example of a mechanism that evolved in nature long before its invention by man and could inspire alternative valve technologies.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent

    Hideo Imamura et al.
    Genome sequencing reveals the evolution and epidemiology of Leishmania donovani in the Indian subcontinent, where epidemics have caused up to 30,000 deaths per year.
    1. Cancer Biology

    Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth

    Kashyap Dave et al.
    A tumor-specific regulatory region has been identified upstream of the Myc oncogene.

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