Diverse sophisticated phylogenetic analyses update the phylogeny of the Alphaproteobacteria and show that the parasitic Holosporales is a derived group within the Rhodospirillales order which comprises primarily free-living alphaproteobacteria.

GABAergic interneurons coordinate synchronous muscle contractions along the length of the fruit fly larva to control the duration between peristaltic waves and locomotion speed.

Independent dating techniques have established that the H. naledi fossils are between 236 and 335 thousand years old, indicating that small-brained hominins with relatively primitive body shapes co-existed with our early ancestors in Africa.

An analysis of the largest Salmonella Typhi genome collection to date (n=13,000) provides an updated overview of global genome diversity and antimicrobial resistance trends over time to inform public health action.

Neurexin–Neuroligin1 complex positively regulates F-actin assembly through direct interaction with WAVE complex to control normal synaptic growth and electrophysiological function in Drosophila neuromuscular junction.

A model of signalling pathways interacting with proneural gene expression explains the sequential patterning of the largest visual processing centre in the developing Drosophila brain.

Pseudogenization of rcsD alters canonical Rcs phosphorelay signalling and marks a significant adaptive evolutionary step in the emergence of ubiquitous extant branches of Yersinia pestis that can maintain stable plague outbreaks.

The transcriptional cofactor HPK-1 (homeodomain-interacting protein kinase) functions as a key regulator of multiple proteostatic stress responses, each originating from discrete neuronal subtypes within the Caenorhabditis elegans nervous system to preserve neuronal health and maintain organismal proteostasis during normal aging.

Coordinated activation and deactivation of inhibitory neurons triggers sequential muscle contractions that enable fruit fly larvae to propel themselves backwards and forwards.

A tumor-specific regulatory region has been identified upstream of the Myc oncogene.