Katie Morris, Edita Bulovaite ... Mathew H Horrocks
PSD95 supercomplexes maintain long-term stability through gradual subunit replacement, with the slowest turnover in cortical synapses associated with memory storage.
Anna-Maria Grob, Hendrik Heinbockel ... Lars Schwabe
Behavioral and neural analyses unravel the angular gyrus’ key role in the prioritization of integrated narratives in memory and the orchestration of theta-frequency reconfigurations underpinning the process of memory integration.
Andy Rampersaud, Jeannette Connerney, David J Waxman
Pulsatile chromatin opening stimulated by naturally-occurring plasma growth hormone pulses is one of two GH-determined mechanisms that establish widespread sex differences in hepatic chromatin accessibility and epigenetic regulation, both closely linked to sex differences in liver gene transcription and function.
Swati Gaikwad, Fardin Ghobakhlou ... Alan G Hinnebusch
A mutant impaired for ribosome recycling exhibits translational reprogramming wherein strong mRNAs outcompete weak mRNAs, also observed when preinitiation complexes are diminished by eIF2α phosphorylation or 40S ribosomal subunit depletion.
Juliette Boeri, Claude Meunier ... Antonny Czarnecki
A simple mechanism, based on the synergy of two major opposing voltage-dependent currents that are ubiquitous in neurons, produces functional diversity of developing Renshaw cells in the embryo.
