An iterative self-assembling algorithm identifies the intrinsic structures in single-cell transcriptomic data and helps to discover new cell populations that are undetectable by existing methods.

Overexpression of VPS9D1-AS1 is a lncRNA to activate TGF-β and IFN signaling pathways, regulates crosstalk between cancer cells and T lymphocytes in the tumor microenvironment.

Naive CD4 and CD8 T cells in mice increase their survival capacity with age, but their numbers are not homeostatically regulated.

Burst-like neural activity in the β-frequency band conveys inhibitory commands within long-proposed cortico-subcortical networks for motor inhibition, with inhibitory activity in STN preceding thalamic activity, which has strong implications for movement disorders marked by abnormalities in β-bursting.

Spinal circuits performing speed- and context-dependent control of locomotion in mammals can operate in different regimes with prevailing role of central mechanisms, supraspinal signals, or sensory feedback.

Opioids have distributed effects on the brainstem circuitry that controls breathing, including presynaptic and postsynaptic receptor-mediated inhibition of an excitatory circuit from the dorsolateral pons to the ventrolateral medulla.

PIK3R1 mutations that cause immunodeficiency through PI3-kinase hyperactivation also cause SHORT syndrome, due to PI3-kinase hypofunction, attributable to PI3-kinase destabilisation and outcompetition by mutant PIK3R1.

A theoretical model that uses maximally informative spectrotemporal features to classify vocalizations, trained solely on natural guinea pig vocalizations, predicts guinea pig behavioral performance in classifying natural as well as spectrotemporally manipulated vocalizations.

Exceptionally long-lived macromolecules in mammalian ovaries and oocytes serve as pillars for lifelong reproductive health span.

A novel technology for recording muscle activity provides unprecedented access to the electrical signals that control the body across muscles, species, and behaviors.