1,682 results found
    1. Computational and Systems Biology

    Inequalities in the distribution of National Institutes of Health research project grant funding

    Michael S Lauer, Deepshikha Roychowdhury
    Funding inequalities for NIH-supported research project grant investigators and organizations have increased over the past 25 years, but have modestly decreased over the past 3 years.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Endothelial pannexin 1–TRPV4 channel signaling lowers pulmonary arterial pressure in mice

    Zdravka Daneva et al.
    Endothelial pannexin 1-P2Y2 purinergic receptor-TRPV4 channel signaling, facilitated by caveolin-1, is a novel pathway for lowering pulmonary arterial pressure.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    Characterizing human mobility patterns in rural settings of sub-Saharan Africa

    Hannah R Meredith et al.
    Mobile phone data reveal aspects of human mobility patterns in Sub-Saharan Africa missed by standard spatial models however, model estimates can be improved by accounting for trip urbanicity and region.
    1. Immunology and Inflammation

    Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells

    Anders Laustsen et al.
    Probing of various culture conditions leads to fundamental advances in ex vivo production of plasmacytoid dendritic cells for use in immunotherapy.
    1. Evolutionary Biology
    2. Physics of Living Systems

    A framework for studying behavioral evolution by reconstructing ancestral repertoires

    Damián G Hernández et al.
    The behavioral repertoires from six species of flies are measured, and a statistical approach is developed to predict co-evolving behaviors, providing a potential framework for exploring behavioral evolution.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation

    Teresa Romeo Luperchio et al.
    Chromatin/transcriptome profiling in multiple mouse models with mutations in epigenetic machinery (EM) reveals shared abnormalities including many IgA-relevant genes, indicating that this kind of joint analysis may elucidate the multigenic nature of EM disorders.
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Drosophila STING protein has a role in lipid metabolism

    Katarina Akhmetova et al.
    Drosophila STING protein, or stimulator of interferon genes, has a direct but previously unknown role in the lipid metabolism.
    1. Computational and Systems Biology
    2. Neuroscience

    Continuous attractors for dynamic memories

    Davide Spalla et al.
    A neural network model with asymmetric synaptic interactions can store and retrieve multiple continuous memory sequences with their temporal structure.
    1. Structural Biology and Molecular Biophysics

    Hsp40s play complementary roles in the prevention of tau amyloid formation

    Rose Irwin et al.
    Chaperones from different families and classes synergistically target different stages of tau aggregation, thus preventing pathological amyloid formation.
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    Addressing shortfalls of laboratory HbA1c using a model that incorporates red cell lifespan

    Yongjin Xu et al.
    The person-specific adjusted HbA1c addresses non-glycaemic variation in laboratory HbA1c due to red blood cell lifespan differences, potentially providing a better marker to predict diabetes complications and guide glycaemic management.

Refine your results by:

Type
Research categories