Compared with the approach isolating COVID-19 patients for a fixed period, the approach using repeated PCR testing mitigates unnecessarily lengthy isolation of patients while minimizing the risk of further transmission.
Ryoji Amamoto, Mauricio D Garcia ... Constance L Cepko
Probe-Seq is a cell type specific bulk RNA sequencing method that can be applied to a wide-ranging tissue types from both vertebrates and invertebrates without genetic labeling.
A photoconversion-based isolation technique enables systematic investigation of spatially distinct small metastases (microcolonies) versus large lesions (macrometastases).
Oxytocin neurons in the paraventricular nucleus of the hypothalamus mediate the increased sociability as a consequence of acute social isolation during adolescence via ventral tegmental area circuits.
Site-specific modification of NEMO facilitates RANKL signal specificity in myeloid progenitors and serves as a potential target to modulate inflammatory osteolysis through ISG15-dependent autophagy.
Serotonin neurons in chronically isolated mice become less responsive to excitatory stimulation, but inhibiting a distinctive calcium-activated potassium channel can restore both neuronal activity and behavior.
Dmitry Ter-Ovanesyan, Maia Norman ... David R Walt
Measuring surface proteins on extracellular vesicles enables quantitative comparison of different isolation methods and optimization of size exclusion chromatography.
Lilliana Radoshevich, Francis Impens ... Pascale Cossart
The induction of ISG15 during bacterial infection can be independent of Type I Interferons and leads to an increase in the secretion of cytokines known to be critical for bacterial clearance.