Sean V Connelly, Nicholas F Brazeau ... Jeffrey A Bailey
Parasite migration between mainland Tanzania and Zanzibar and ongoing transmission clusters within Zanzibar highlight the need for continued preventive measures to reduce malaria transmission in the archipelago.
Atg43 serves as a selective autophagy receptor by tethering isolation membranes to mitochondria to promote mitophagy and plays a mitophagy-independent role that facilitates normal cell growth in fission yeast.
A novel immunoassay for ApoB-100, the main protein component of lipoproteins, enables the development of methods to enrich extracellular vesicles from human plasma while depleting both lipoproteins and free proteins.
MakA, a pore-forming cytotoxin produced by Vibrio cholerae, forms oligomers and remodels membranes into high-curvature tubes, resulting in membrane integrity loss inside acidified organelle lumens or when cultured with cells in an acidic medium.
Laura Ferrer-Font, Palak Mehta ... Johannes U Mayer
A systematic optimization of intestinal digestion protocols allows for the isolation and high-dimensional flow cytometric analysis of intestinal immune cells during murine helminth infection.
Oligomerization of p62/SQSTM1 generates high avidity binding regions that enable it to spatially select for concentrated ubiquitin and ATG8-family proteins.
In juvenile songbirds, neural sequences pre-exist tutor exposure, and the process of learning a new song may make use of existing neural sequences as a stable substrate for new behavioral changes.
Two GAP proteins bound to mitochondria regulate the enyzme Rab7, and thereby the expansion of the isolation membrane during mitophagy, downstream of PINK1 and Parkin, two proteins that are mutated in familial Parkinson's disease.
