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The fusion of astronomy and cellular cardiology reveals the 3D arrangement and the firing reliability of active excitation-contraction coupling sites in beating cardiac myocytes.

Neural dynamics during prior experience-guided visual ambiguity resolution reveal early stimulus-feature processing and late content-specific recognition processing involving large-scale brain networks.

The timing and outcome of mammalian cell lineage decisions can be controlled by slow, stochastic events on individual regulatory gene loci.

Imaging of structure and function in the brain from thousands of participants was used along with genetics and biophysical measures to study many different aspects of how the brain ages.

A novel quantitative framework to analyse the inner structure of tumour spheroids in terms of the mechanisms that underly growth.

Retrograde signaling activates the Rad53 checkpoint kinase independently of the canonical DNA replication stress response.

Peripheral retinal input transiently amplifies information transmission from ganglion cells, dynamically allocating the resources of neural activity to times of expected high information content.

A noisy cell-intrinsic timer provides positional information for the segmentation clock, modulated by extrinsic factors such as FGF.

Mars provides a software platform for the development of complex single-molecule analysis workflows enabling the discovery and reporting of new biological phenomena with an open data format accessible to everyone.

Neural network modeling shows that hierarchical application of the simple computational principle of predicting future sensory input from its past can capture features of visual motion processing from the retina to the visual cortex.