15,840 results found
    1. Cell Biology

    Ezrin defines TSC complex activation at endosomal compartments through EGFR-AKT signaling

    Giuliana Giamundo, Daniela Intartaglia ... Ivan Conte
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Developmental Biology

    Tgfbr1 regulates lateral plate mesoderm and endoderm reorganization during the trunk to tail transition

    Anastasiia Lozovska, Ana Casaca ... Moises Mallo
    Tgfbr1 signaling governs all processes associated with the trunk to tail transition, including the repositioning of neuro-mesodermal progenitors, as well as the remodeling of the lateral plate mesoderm and embryonic endoderm.
    1. Cell Biology

    Progesterone induces meiosis through two obligate co-receptors with PLA2 activity

    Nancy Nader, Lama Assaf ... Khaled Machaca
    Progesterone mediates nongenomic signaling in Xenopus oocyte meiosis by activating a PLA2 activity that requires two membrane receptors ABDH2 and mPRß.
    1. Neuroscience

    Operation of spinal sensorimotor circuits controlling phase durations during tied-belt and split-belt locomotion after a lateral thoracic hemisection

    Ilya A Rybak, Natalia A Shevtsova ... Alain Frigon
    Computational modeling based on experimental data reveals how spinal sensorimotor circuits control cycle and phase durations during treadmill locomotion after an incomplete spinal cord injury.
    1. Ecology

    Combining radio-telemetry and radar measurements to test optimal foraging in an aerial insectivore bird

    Itai Bloch, David Troupin ... Nir Sapir
    Little Swifts dynamically adjust their foraging behavior to aerial insect abundance, revealing key insights into predator–prey interactions and optimal foraging strategies in aerial environments.
    1. Neuroscience
    2. Physics of Living Systems

    A Deep Learning Pipeline for Mapping in situ Network-level Neurovascular Coupling in Multi-photon Fluorescence Microscopy

    Matthew Rozak, James Mester ... Bojana Stefanovic
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
    1. Genetics and Genomics

    Dynamics and regulatory roles of RNA m6A methylation in unbalanced genomes

    Shuai Zhang, Ruixue Wang ... Lin Sun
    Global analyses using aneuploid Drosophila revealed the dynamic roles of RNA m6A modification in regulating gene expression and development under genomic imbalance, highlighting its potential relationships with dosage-related effects.
    1. Neuroscience

    Automated cell annotation in multi-cell images using an improved CRF_ID algorithm

    Hyun Jee Lee, Jingting Liang ... Hang Lu
    Highly accurate automated cell annotation in multi-cell imaging enables cell identification and reduces subjectivity in Caenorhabditis elegans neural image processing.
    1. Neuroscience

    A split-GAL4 driver line resource for Drosophila neuron types

    Geoffrey W Meissner, Allison Vannan ... FlyLight Project Team
    Thousands of cell-type-specific split-GAL4 driver lines and a massive, searchable image collection enable Drosophila neuroscientists to target neurons of interest with increased precision.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Risk factors affecting polygenic score performance across diverse cohorts

    Daniel Hui, Scott Dudek ... Marylyn D Ritchie
    Numerous related sample characteristics affect polygenic score performance, and incorporation of interaction effects increases both model and polygenic score performance.

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