Verena Pawlak, David S Greenberg ... Jason ND Kerr
Changing the order in which presynaptic and postsynaptic cells are repeatedly activated can change what a mammalian visual cortex neuron communicates to downstream neurons.
Meaghan Castledine, Daniel Padfield ... Angus Buckling
Parallel evolutionary dynamics were found in vivo and in vitro, showing that laboratory studies can be predictive of certain phenotypic outcomes of clinical phage therapy (phage-mediated decolonization).
Direct in-vivo measurements in the human brain test validity of detailed computational models of trancranial electric stimulation and show that electric fields in the brain are weaker than currently assumed.
Experimental manipulations and a mechanical model of the fiber reveal that the Reissner fiber is under heterogenous tension in vivo, and interacts with the motile cilia of diverse cells contacting the cerebrospinal fluid.
During parallel fibre activity in vivo, postsynaptic mGluR1 receptors in molecular layer interneurons of the cerebellar cortex are engaged in a frequency-dependent manner and in concert with inotropic glutamate receptors.
A high-throughput functional validation system for large numbers of candidate disease genes enables in vivo functional testing of specific gene variants.
Suhasa B Kodandaramaiah, Francisco J Flores ... Craig R Forest
A robot capable of automatically obtaining blind whole cell patch clamp recordings from multiple neurons simultaneously guides four interacting electrodes in a coordinated fashion, avoiding mechanical coupling in the brain.