8 results found
    1. Microbiology and Infectious Disease
    2. Neuroscience

    Microbiota regulates visceral pain in the mouse

    Pauline Luczynski et al.
    Determining that microbiota-deficient mice have increased visceral pain, which can be reversed by restoring microbiota, may lead to novel microbial-based strategies for disorders associated with visceral pain.
    1. Neuroscience

    Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior

    Mar Gacias et al.
    Gut microbiota can influence mPFC transcriptional profiles and myelin content, overriding the impact of genetic background in the development of social avoidance behavior.
    1. Computational and Systems Biology
    2. Neuroscience

    The periaqueductal gray and Bayesian integration in placebo analgesia

    Arvina Grahl et al.
    Bayesian integration is able to predict placebo treatment outcomes by focusing especially on the influence of the precision of expectations.
    1. Immunology and Inflammation

    Brain micro-inflammation at specific vessels dysregulates organ-homeostasis via the activation of a new neural circuit

    Yasunobu Arima et al.
    A link between chronic stress and organ dysfunction is explained by the gateway reflex, in which brain micro-inflammation at specific vessels establishes a new neural pathway to induce fatal organ failure particularly in gastrointestine and heart.
  1. June roundup of eLife papers in the news

    Showcasing the top mentions that eLife papers received in June.
    1. Neuroscience

    Regional complexity in enteric neuron wiring reflects diversity of motility patterns in the mouse large intestine

    Zhiling Li et al.
    Calcium response profiling of large populations of enteric neurons reveals hard-wired neural circuits that reflect the motility program portfolio of the intestinal region they occupy.
    1. Human Biology and Medicine
    2. Neuroscience

    A Cryptochrome 2 mutation yields advanced sleep phase in humans

    Arisa Hirano et al.
    A missense mutation in the human Cryptochrome 2 (CRY2) gene leads to the condition of familial advanced sleep phase.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    The genetic architecture of NAFLD among inbred strains of mice

    Simon T Hui et al.
    A system genetics approach reveals a unique molecular signature of non-alcoholic fatty liver disease in mice and identifies novel genetic factors affecting hepatic steatosis.

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