Height in early adulthood is an indicator that integrates across different dimensions of sustainable human development with links to health and longevity, nutrition, education and economic productivity.
Measuring HIV-1 DNA levels at the time of stopping antiretroviral therapy (when initiated during primary infection) predicts clinical progression and the time taken for plasma viraemia to become detectable.
The findings have a major impact in understanding the different reward systems involved in two types of addictive behavior, and these advances have implications for prevention and treatment.
Single-molecule analysis of SARS-CoV-2 RNA identifies significant heterogeneity in cellular viral RNA levels and highlights slower replication kinetics for the Alpha variant compared to the Victoria strain.
Trajectories of adolescent drinking behavior between age 14 and 19 years can be predicted from bilateral striatal and cerebellar grey matter at 14 years of age.
Embryonic fate-mapping approaches in zebrafish, Xenopus and lamprey illuminate the evolutionary origins of carotid body glomus cells and pulmonary neuroendocrine cells.
Ricardo Guerrero-Ferreira, Nicholas MI Taylor ... Henning Stahlberg
Two new polymorphic structures of recombinant human alpha-synuclein fibrils show striking differences to previous structures, while familial PD mutation sites remain crucial for protofilament interaction and fibril stability.
Barbara H Stokes, Satish K Dhingra ... David A Fidock
Plasmodium falciparum K13 mutations confer resistance to the antimalarial artemisinin in Asian and African parasites, with most gene-edited mutant K13 African parasite lines showing a fitness cost that may predict slow dissemination of artemisinin resistance in high-transmission settings.
Ethan Knights, Richard N Henson ... Kamen A Tsvetanov
Older people can recruit additional brain regions to help perform complex tasks, possibly compensating for age-related changes in other parts of the brain.