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    1. Neuroscience

    Visual attention is available at a task-relevant location rapidly after a saccade

    Tao Yao, Madhura Ketkar ... B Suresh Krishna
    Spatial attention and saccadic processing co-ordinate to ensure that attention is available at a task-relevant location soon after the beginning of each eye fixation.
    1. Neuroscience

    Extracting grid cell characteristics from place cell inputs using non-negative principal component analysis

    Yedidyah Dordek, Daniel Soudry ... Dori Derdikman
    Computational modeling of the brain’s navigation system reveals that place cells can drive the formation of hexagonal patterns experimentally observed in grid cells activity.
    1. Neuroscience

    Filopodial dynamics and growth cone stabilization in Drosophila visual circuit development

    Mehmet Neset Özel, Marion Langen ... P Robin Hiesinger
    Long-term live imaging in intact developing Drosophila brains reveals a role for N-Cadherin-mediated fast filopodial dynamics and growth cone stabilization during neural circuit assembly.
    1. Structural Biology and Molecular Biophysics

    Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography

    Daniel A Keedy, Lillian R Kenner ... James S Fraser
    The conformations of the enzyme cyclophilin A that are essential for its catalytic activity are temperature dependent and exhibit diverse responses, which is consistent with a complex energy landscape.
    1. Ecology

    Strong biomechanical relationships bias the tempo and mode of morphological evolution

    Martha M Muñoz, Y Hu ... SN Patek
    The rules of biomechanics consistently influence the tempo (rate) and mode (pattern) of evolution across four-bar linkage systems in animals.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Meta-Research: COVID-19 research risks ignoring important host genes due to pre-established research patterns

    Thomas Stoeger, Luís A Nunes Amaral
    An analysis of 10,395 research publications about COVID-19 that mention at least one human gene reveals that many genes implicated in SARS-CoV-2 infection by genome-wide studies remain unstudied.
    1. Developmental Biology
    2. Neuroscience

    Unc-4 acts to promote neuronal identity and development of the take-off circuit in the Drosophila CNS

    Haluk Lacin, W Ryan Williamson ... James W Truman
    Unc-4 acts in a lineage-specific manner to promote different neuronal fates and locomotion behavior in Drosophila.
    1. Neuroscience

    Light sets the brain’s daily clock by regional quickening and slowing of the molecular clockworks at dawn and dusk

    Suil Kim, Douglas G McMahon
    Light signals adjusting the brain's daily clock induce distinct waveform changes in molecular clock gene rhythms at dawn and dusk, and trigger regionally differential clock changes.
    1. Structural Biology and Molecular Biophysics
    2. Evolutionary Biology

    Methylation at the C-2 position of hopanoids increases rigidity in native bacterial membranes

    Chia-Hung Wu, Maja Bialecka-Fornal, Dianne K Newman
    Methylation specifically enhances the ability of hopanoids to rigidify membranes under physiologically relevant conditions, which impacts the current interpretation of the 2-methylhopane fossil record.
    1. Chromosomes and Gene Expression

    Single-molecule imaging of chromatin remodelers reveals role of ATPase in promoting fast kinetics of target search and dissociation from chromatin

    Jee Min Kim, Pat Visanpattanasin ... Carl Wu
    Chromatin remodeling enzymes perform target search by utilizing ATP-binding and hydrolysis to facilitate 1D-diffusion on and rapid detachment from chromatin in living yeast.