A single amino acid change in a neuronal ion channel called KCNQ2 blocks ion flow, prevents protein localization on axons, and results in severe epilepsy and slowed neurological development.

Kiss1^ARH neurons transition from synchronous to burst firing under preovulatory levels of E2, causing a shift from peptidergic to glutamatergic transmission that drives the GnRH surge through enhanced glutamate neurotransmission.

A striking and consequential conductance in vestibular type I hair cells is finally shown to depend on a little-known Shaker subunit that contributes to conventional conductances in other hair cells.

Aging reduces the potassium M current in sympathetic motor neurons, resulting in a hyperactive phenotype that can be reversed by pharmacological activation of these channels.

Circuit-based intervention corrects irreconcilable excitability defects between dentate granule cells and mossy cells in Fmr1 knockout mice, representing a promising strategy to restore the dentate excitation/inhibition balance and circuit computations.

Molecular and electrophysiological evidence shows that Kv3 subunits contribute critically to ultrashort action potential waveforms and high-frequency firing in large projection neurons in zebra finch motor nuclei controlling song production and somatic movements.

Calmodulin mediates in the protective augmentation of K_V7-currents in response to oxidative stress in a calcium-dependent manner by an unconventional signaling mechanism.

The processing of light and dark contrast information for detecting impending visual threats within grasshopper neurons reveals new mechanisms of information processing in the brain.